Caferova Sahnaz, Uysal Fatma, Balcı Pınar, Saydam Serdar, Canda Tülay
Department of Radiology, Dokuz Eylül University, Izmir, Turkey.
Department of Radiology, Dokuz Eylül University, Izmir, Turkey ; Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
Contemp Oncol (Pozn). 2014;18(3):197-203. doi: 10.5114/wo.2014.42721. Epub 2014 May 20.
The aim of this study is to research the contribution of radiothermometry (RTM) to the characterization of breast masses, the differentiation of malignant-benign masses and diagnosis of early stage breast cancer.
This prospective study comprised 182 cases of patients diagnosed with a breast mass and a control group of 55 cases: a total of 237.
When histopathology is accepted as the gold standard among diagnostic methods, the sensitivity, specificity, and positive-negative predictive value for RTM were 90.9%, 20.8%, 61.2% and 62.5%, respectively. Consistency was 0.129. When compared with mammography the same values for RTM examination are 87%, 81.4%, 58% and 95.5%. Consistency was 0.582. Evaluating with respect to size of the mass accepting mammography as the gold standard, RTM examination had sensitivity, specificity, positive and negative predictive values for masses 2 cm and above of 88.9%, 83.3%, 88.9% and 83.3%. Consistency was 0.722. The consistency of RTM for lesion diagnosis in BI-RADS II breast structure is higher than the consistency of mammography.
Identification of lesions in the breast and presence of microcalcification by RTM shows that it is more trustworthy compared to mammography. When compared with mammography the validity results for RTM show there is a good level of conformity between the two methods. When evaluated based on the area below the ROC cure and compared to mammography, RTM is sufficiently successful at evaluating positive and negative cases.
本研究旨在探讨放射热测定法（RTM）在乳腺肿块特征描述、良恶性肿块鉴别及早期乳腺癌诊断中的作用。
本前瞻性研究包括182例诊断为乳腺肿块的患者及55例对照组，共237例。
以组织病理学作为诊断方法中的金标准时，RTM的敏感性、特异性、阳性和阴性预测值分别为90.9%、20.8%、61.2%和62.5%。一致性为0.129。与乳腺X线摄影相比，RTM检查的相应值分别为87%、81.4%、58%和95.5%。一致性为0.582。以乳腺X线摄影为金标准，根据肿块大小评估，RTM检查对2cm及以上肿块的敏感性、特异性、阳性和阴性预测值分别为88.9%、83.3%、88.9%和83.3%。一致性为0.722。RTM对BI-RADS II型乳腺结构中病变诊断的一致性高于乳腺X线摄影。
RTM对乳腺病变的识别及微钙化的显示表明，与乳腺X线摄影相比，它更可靠。与乳腺X线摄影相比，RTM的有效性结果表明两种方法之间具有良好的一致性水平。基于ROC曲线下面积评估并与乳腺X线摄影相比，RTM在评估阳性和阴性病例方面足够成功。
