伊朗东南部扎黑丹血友病患者的乙型和丙型肝炎病毒感染
Hepatitis B and C virus infections in patients with hemophilia in Zahedan, southeast Iran.
作者信息
Sharifi-Mood Batool, Eshghi Payman, Sanei-Moghaddam Esmail, Hashemi Mohammad
机构信息
Research Center for Infectious Diseases and Tropical Medicine, Boo-Ali Hospital, Zahedan University of Medical Sciences, Zahedan, Iran.
出版信息
Saudi Med J. 2007 Oct;28(10):1516-9.
OBJECTIVE
To determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in patients with hemophilia in Zahedan, Iran.
METHODS
From March 2003 to January 2006, we evaluated 81 hemophiliac patients in Zahedan Hemophilia Center, southeast Iran, for hepatitis C virus antibody (HCV-Ab) and hepatitis B surface antigen (HBsAg), and evaluated the prevalence of HBV/HCV co-infection.
RESULTS
The seroprevalence of HCV was 29.6%, and the HBsAg was positive in 4.9%. Four cases had HCV and HBV co-infection. All of the infected patients were unknowingly treated with contaminated plasma products before the middle of 1996.
CONCLUSION
All hemophiliacs, especially patients who have been treated with unheated clotting factor concentrates, should be evaluated for HCV and HBV infections.
目的
确定伊朗扎黑丹血友病患者中乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）感染的患病率。
方法
2003年3月至2006年1月，我们对伊朗东南部扎黑丹血友病中心的81例血友病患者进行了丙型肝炎病毒抗体（HCV-Ab）和乙型肝炎表面抗原（HBsAg）检测，并评估了HBV/HCV合并感染的患病率。
结果
HCV血清阳性率为29.6%，HBsAg阳性率为4.9%。4例患者同时感染了HCV和HBV。所有感染患者在1996年年中之前均在不知情的情况下接受了受污染的血浆制品治疗。
结论
所有血友病患者，尤其是接受过未加热凝血因子浓缩物治疗的患者，均应进行HCV和HBV感染评估。
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