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瑞典儿童和青少年的慢性炎症性肠病

Chronic inflammatory bowel disease in children and adolescents in Sweden.

作者信息

Hildebrand H, Fredrikzon B, Holmquist L, Kristiansson B, Lindquist B

出版信息

J Pediatr Gastroenterol Nutr. 1991 Oct;13(3):293-7. doi: 10.1097/00005176-199110000-00010.

DOI:10.1097/00005176-199110000-00010
PMID:1791507
Abstract

The incidence and prevalence of chronic inflammatory bowel disease (IBD) in children was established during 1984 and 1985 in a prospective study in Sweden. The patients with IBD were classified as having ulcerative colitis (UC), Crohn's disease (CD), probable Crohn's disease (PCD), and indeterminate colitis (IC) according to defined histopathologic, endoscopic, and radiologic criteria. The study covered 1.51 million children less than 16 years of age (93% of all children in Sweden). The incidence of IBD was 5.0 and 4.5 and the prevalence was 17.6 and 18.2 per 100,000 children during the 2 years, respectively. The mean prevalence of UC was 7.5 per 100,000 and of CD + PCD was 6.2 per 100,000. The prevalence of IC was 4.2 per 100,000, which corresponds to 23% of the children with IBD.

摘要

1984年至1985年期间,在瑞典的一项前瞻性研究中确定了儿童慢性炎症性肠病(IBD)的发病率和患病率。根据明确的组织病理学、内镜检查和放射学标准,将IBD患者分为溃疡性结肠炎(UC)、克罗恩病(CD)、疑似克罗恩病(PCD)和不确定性结肠炎(IC)。该研究涵盖了151万名16岁以下儿童(占瑞典所有儿童的93%)。在这两年中,IBD的发病率分别为每10万名儿童5.0例和4.5例,患病率分别为每10万名儿童17.6例和18.2例。UC的平均患病率为每10万名儿童7.5例,CD + PCD的平均患病率为每10万名儿童6.2例。IC的患病率为每10万名儿童4.2例,占IBD患儿的23%。

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