Eriksson Charlotta, Rosenlund Mats, Pershagen Göran, Hilding Agneta, Ostenson Claes-Göran, Bluhm Gösta
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Epidemiology. 2007 Nov;18(6):716-21. doi: 10.1097/EDE.0b013e3181567e77.
An association between aircraft noise exposure and hypertension prevalence has been suggested but there are no longitudinal studies of this association. Our aim was to investigate the influence of aircraft noise on the incidence of hypertension.
A cohort of 2754 men in 4 municipalities around Stockholm Arlanda airport was followed between 1992-1994 and 2002-2004. The cohort was based on the Stockholm Diabetes Preventive Program; half of the study subjects had a family history of diabetes. Residential aircraft noise exposure (expressed as time-weighted equal energy and maximal noise levels) was assessed by geographical information systems techniques among those living near the airport. Incident cases of hypertension were identified by physical examinations, including blood pressure measurements, and questionnaires in which subjects reported treatment or diagnosis of hypertension and information on cardiovascular risk factors. Analyses were restricted to 2027 subjects who completed the follow-up examination, were not treated for hypertension, and had a blood pressure below 140/90 mm Hg at enrollment.
For subjects exposed to energy-averaged levels above 50 dB(A) the adjusted relative risk for hypertension was 1.19 (95% CI = 1.03-1.37). Maximum aircraft noise levels presented similar results, with a relative risk of 1.20 (1.03-1.40) for those exposed above 70 dB(A). Stronger associations were suggested among older subjects, those with a normal glucose tolerance, nonsmokers, and subjects not annoyed by noise from other sources.
These findings suggest that long-term aircraft noise exposure may increase the risk for hypertension.
已有研究表明飞机噪声暴露与高血压患病率之间存在关联,但尚无关于此关联的纵向研究。我们的目的是调查飞机噪声对高血压发病率的影响。
1992年至1994年以及2002年至2004年期间,对斯德哥尔摩阿兰达机场周边4个直辖市的2754名男性进行了队列研究。该队列基于斯德哥尔摩糖尿病预防项目;一半的研究对象有糖尿病家族史。通过地理信息系统技术评估了居住在机场附近人群的飞机噪声暴露情况(以时间加权等效能量和最大噪声水平表示)。通过体格检查(包括血压测量)以及问卷调查确定高血压发病病例,问卷中受试者报告高血压的治疗或诊断情况以及心血管危险因素信息。分析仅限于2027名完成随访检查、未接受高血压治疗且入组时血压低于140/90 mmHg的受试者。
对于暴露于能量平均水平高于50 dB(A)的受试者,高血压的校正相对风险为1.19(95%置信区间 = 1.03 - 1.37)。最大飞机噪声水平呈现类似结果,暴露于70 dB(A)以上的受试者相对风险为1.20(1.03 - 1.40)。在老年受试者、糖耐量正常者、不吸烟者以及未受到其他来源噪声干扰的受试者中,关联更为明显。
这些发现表明长期暴露于飞机噪声可能会增加患高血压的风险。