Sbihi H, Davies H W, Demers P A
University of British Columbia, Vancouver, Canada.
Occup Environ Med. 2008 Sep;65(9):643-6. doi: 10.1136/oem.2007.035709. Epub 2008 Jan 4.
To investigate the hypothesised association between exposure to high levels of noise and risk of hypertension using quantitative exposure assessment and administrative health data.
This study followed a cohort of 10 872 sawmill workers in British Columbia from 1991 to 1998. Subjects were linked with provincial hospital discharge, outpatient and vital status databases. Cases were males who died, had at least one hospital admission, or who had three doctor visits within 70 days, for hypertension (ICD-9 codes 401-405). We used four exposure metrics: cumulative exposure, and duration of exposure above thresholds of 85 dBA, 90 dBA and 95 dBA. Relative risks were estimated using Poisson regression with the low-exposure group as controls and adjusting for age, ethnicity and calendar period.
828 cases were identified. The results showed a monotonic increase in hypertension incidence with cumulative exposure. The risk in the highest exposed population was 32% higher than baseline. Similar results were found using duration of exposure metrics. The highest relative risk was 1.5 in workers exposed for more than 30 years at 85 dBA. Exposure-response trends were statistically significant.
The risk of hypertension was positively associated with noise exposure above 85 dB.
运用定量暴露评估和行政健康数据,研究高水平噪声暴露与高血压风险之间的假设关联。
本研究追踪了1991年至1998年不列颠哥伦比亚省的10872名锯木厂工人队列。研究对象与省级医院出院、门诊和生命状况数据库相链接。病例为因高血压(国际疾病分类第九版编码401 - 405)死亡、至少有一次住院治疗或在70天内有三次就诊记录的男性。我们使用了四种暴露指标:累积暴露,以及暴露于85分贝、90分贝和95分贝阈值以上的持续时间。以低暴露组为对照,采用泊松回归估计相对风险,并对年龄、种族和日历时间进行调整。
共识别出828例病例。结果显示,高血压发病率随累积暴露呈单调增加。最高暴露人群的风险比基线高32%。使用暴露持续时间指标也发现了类似结果。在85分贝下暴露超过30年的工人中,最高相对风险为1.5。暴露 - 反应趋势具有统计学意义。
85分贝以上的噪声暴露与高血压风险呈正相关。