Hobert Oliver
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, NY 10032, USA.
Cell. 2007 Oct 5;131(1):22-4. doi: 10.1016/j.cell.2007.09.031.
Two new studies describe functionally relevant interactions between microRNAs (miRNAs) and their targets in the immune system and the brain (Xiao et al., 2007; Karres et al., 2007). Furthermore, these studies illustrate the involvement of miRNAs in tuning the expression of target genes to physiologically relevant levels.
两项新研究描述了微小RNA(miRNA)与其在免疫系统和大脑中的靶标之间功能上相关的相互作用(Xiao等人,2007年;Karres等人,2007年)。此外,这些研究表明miRNA参与将靶基因的表达调节至生理相关水平。