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[测定羧苄青霉素对铜绿假单胞菌活性的各种方法]

[Various methods to assay carbenicillin activity against Pseudomonas aeruginosa].

作者信息

Litovchenko P P, Dekhtiar N V, Keĭsevich L V, Lukach I G

出版信息

Antibiot Khimioter. 1991 Nov;36(11):17-21.

PMID:1793288
Abstract

It was shown that the cultures of Pseudomonas aeruginosa were sensitive to 75-100 micrograms/ml and resistant to 25-50 micrograms/ml of carbenicillin when tested by the method of serial dilutions in the synthetic medium developed by the authors and in Jorgensen's medium. The cultures were incubated for 4 and 16 hours, respectively. The data did not confirm the resistance of the cultures to 25-75 and 100 micrograms/ml carbenicillin when it was determined with the serial dilution method in Pal's medium and the disk diffusion method, respectively. The advantages of the medium developed by the authors for testing P. aeruginosa sensitivity to carbenicillin are discussed.

摘要

结果表明,当采用作者开发的合成培养基和约根森培养基中的连续稀释法进行测试时,铜绿假单胞菌培养物对75 - 100微克/毫升的羧苄青霉素敏感,而对25 - 50微克/毫升的羧苄青霉素耐药。培养物分别孵育4小时和16小时。当分别用帕尔培养基中的连续稀释法和纸片扩散法测定时,数据并未证实培养物对25 - 75微克/毫升和100微克/毫升羧苄青霉素耐药。文中讨论了作者开发的用于测试铜绿假单胞菌对羧苄青霉素敏感性的培养基的优点。

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1
[Various methods to assay carbenicillin activity against Pseudomonas aeruginosa].[测定羧苄青霉素对铜绿假单胞菌活性的各种方法]
Antibiot Khimioter. 1991 Nov;36(11):17-21.
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