Abrahams Ronald R, Kelly S Ann, Payne Sarah, Thiessen Paul N, Mackintosh Jessica, Janssen Patricia A
UBC Department of Health Care and Epidemiology, 5804 Fairview Ave, Vancouver, BC.
Can Fam Physician. 2007 Oct;53(10):1722-30.
To evaluate the effect of rooming-in (rather than standard nursery care) on the incidence and severity of neonatal abstinence syndrome among opioid-exposed newborns and on the proportion of mothers who retain custody of their babies at hospital discharge.
Retrospective cohort study.
Lower mainland in southwestern British Columbia.
We selected 32 women in the city of Vancouver known to have used heroin or methadone during pregnancy between October 2001 and December 2002. Comparison groups were a historical cohort of 38 women in Vancouver and a concurrent cohort of 36 women cared for in a neighbouring community hospital.
Need for treatment with morphine, number of days of treatment with morphine, and whether babies were discharged in the custody of their mothers.
Rooming-in was associated with a significant decrease in need for treatment of neonatal abstinence syndrome compared with the historical cohort (adjusted relative risk [RR] 0.40, 95% confidence interval [CI] 0.20 to 0.78) and the concurrent cohort (adjusted RR 0.39, 95% CI 0.20 to 0.75). Rooming-in was also associated with shorter newborn length of stay in hospital compared with both comparison groups. Newborns who roomed in at BC Women's Hospital were significantly more likely to be discharged in the custody of their mothers than babies in the historical cohort (RR 2.23, 95% CI 1.43 to 3.98) or the concurrent cohort (RR 1.52, 95% CI 1.15 to 2.53) were.
Rooming-in might ease opioid-exposed newborns' transition to extrauterine life and promote more effective mothering.
评估母婴同室（而非标准的新生儿护理）对阿片类药物暴露新生儿戒断综合征的发病率和严重程度，以及对出院时保留婴儿监护权的母亲比例的影响。
回顾性队列研究。
不列颠哥伦比亚省西南部的低陆平原。
我们选取了2001年10月至2002年12月期间在温哥华市已知孕期使用过海洛因或美沙酮的32名女性。对照组为温哥华市38名女性的历史队列以及在邻近社区医院接受护理的36名女性的同期队列。
吗啡治疗需求、吗啡治疗天数，以及婴儿是否在母亲监护下出院。
与历史队列（调整相对风险[RR] 0.40，95%置信区间[CI] 0.20至0.78）和同期队列（调整RR 0.39，95% CI 0.20至0.75）相比，母婴同室与新生儿戒断综合征治疗需求的显著降低相关。与两个对照组相比，母婴同室还与新生儿住院时间缩短相关。在不列颠哥伦比亚妇女医院母婴同室的新生儿在母亲监护下出院的可能性显著高于历史队列（RR为2.23，95% CI为1.43至3.98）或同期队列（RR为1.52，95% CI为1.15至2.53）的婴儿。
母婴同室可能会缓解阿片类药物暴露新生儿向宫外生活的过渡，并促进更有效的母婴关系。
