Arnett Michael V, Lim Julia T
Department of Medicine, Tripler Army Medical Center, MCHK-DM, 1 Jarrett White Road, Honolulu, HI 96859, USA.
Mil Med. 2007 Sep;172(9):1012-5. doi: 10.7205/milmed.172.9.1012.
Ciguatera toxin is a marine neurotoxin produced by microorganisms that becomes concentrated in predatory fish. Toxicity in humans results from the ingestion of contaminated fish harvested in tropical waters. Clinical manifestations of illness include the rapid onset of gastrointestinal symptoms and neurological abnormalities. Because of the rapid onset of symptoms and the potential for case clusters from a common source ingestion of contaminated fish, there is the potential that ciguatera poisoning may initially mimic illnesses caused by antipersonnel biological and chemical agents. We present data on an active duty soldier who presented to sick call for evaluation of new onset paresthesias and was diagnosed with ciguatera toxin poisoning. We also present a review of ciguatera poisoning literature with emphasis on the distinguishing features between ciguatoxin and other neurotoxins of military significance.
雪卡毒素是一种由微生物产生的海洋神经毒素,会在掠食性鱼类体内蓄积。人体中毒是由于食用了在热带水域捕获的受污染鱼类。该病的临床表现包括胃肠道症状和神经功能异常的迅速出现。由于症状出现迅速,且因共同食用受污染鱼类可能出现病例聚集,雪卡毒素中毒最初有可能被误诊为杀伤性生物和化学制剂所致疾病。我们报告了一名现役军人的病例,该军人因新发感觉异常前来就诊,被诊断为雪卡毒素中毒。我们还对雪卡毒素中毒的文献进行了综述,重点介绍了雪卡毒素与其他具有军事意义的神经毒素之间的区别。