Bates Gareth W, Light Mark E, Albrecht Markus, Gale Philip A
School of Chemistry, University of Southampton, Southampton, UK.
J Org Chem. 2007 Nov 9;72(23):8921-7. doi: 10.1021/jo701702p. Epub 2007 Oct 16.
A series of 2,7-functionalized indoles have been synthesized with appended amide and/or urea or thiourea groups. Anion complexation studies show a marked difference in the mode of interaction of carboxylates with indole-ureas vs indole-amides.
一系列带有酰胺和/或脲或硫脲基团的2,7-官能化吲哚已被合成。阴离子络合研究表明,羧酸盐与吲哚-脲和吲哚-酰胺的相互作用模式存在显著差异。