Mathei Jan, Coosemans Willy, Nafteux Philippe, Decker George, De Leyn Paul, Van Raemdonck Dirk, Hoffman Ilse, Deboeck Christiane, Proesmans Marijke, Lerut Toni
Thoracic Surgery, University Hospitals Gasthuisberg, 3000, Leuven, Belgium.
Surg Endosc. 2008 Apr;22(4):1054-9. doi: 10.1007/s00464-007-9578-0. Epub 2007 Oct 18.
The laparoscopic Nissen fundoplication has become a frequently performed procedure in infants and children who suffer from gastroesophageal reflux disease (GERD). In this study we describe our 8-year experience with 106 consecutive laparoscopic Nissen fundoplications.
From January 1994 to May 2002, we included 106 consecutive patients (57 neurologically normal (NN) and 49 neurologically impaired (NI)). The indications were symptomatic GERD, pulmonary symptoms or a combination of both. Patient's outcome was assessed by symptom evaluation, technical examinations and a questionnaire.
Mortality was 0% and conversion rate was 2.8%. Major postoperative complications occurred in 12 patients, mostly neurologically impairment. Dysphagia occurred in 23 patients of which 4 required dilatations and 2 a redo Nissen. Gas bloating occurred in 15 children, with spontaneous regression in all. Recurrent pneumopathies were seen in four children. Documented recurrence of reflux occurred in three symptomatic patients. Redo laparoscopic surgery was performed in six patients. A questionnaire was sent to each patient's parents. This showed that most patients had a normal or clearly improved quality of life (93.1% NN, 90.5% NI). Most patients were satisfied with the result and up to 39.5% gave a maximum satisfaction score.
The laparoscopic Nissen fundoplication can safely be performed with a low conversion rate and no surgical mortality in neurologically normal and neurologically impaired children. Neurologically impaired children are more susceptible to per- and postoperative complications. A good quality of life and a high index of satisfaction could be achieved in most patients.
腹腔镜下尼氏胃底折叠术已成为患有胃食管反流病(GERD)的婴幼儿和儿童中经常施行的手术。在本研究中,我们描述了连续106例腹腔镜下尼氏胃底折叠术的8年经验。
从1994年1月至2002年5月,我们纳入了连续106例患者(57例神经功能正常(NN),49例神经功能受损(NI))。手术指征为有症状的GERD、肺部症状或两者兼有。通过症状评估、技术检查和问卷调查对患者的预后进行评估。
死亡率为0%,中转开腹率为2.8%。12例患者发生了主要术后并发症,大多数为神经功能受损。23例患者出现吞咽困难,其中4例需要扩张治疗,2例需要再次行尼氏手术。15例儿童出现气体腹胀,均自行消退。4例儿童出现复发性肺部疾病。3例有症状的患者记录到反流复发。6例患者进行了再次腹腔镜手术。向每位患者的父母发送了一份问卷。结果显示,大多数患者的生活质量正常或明显改善(NN组93.1%,NI组90.5%)。大多数患者对结果满意,高达39.5%的患者给出了最高满意度评分。
在神经功能正常和神经功能受损的儿童中,腹腔镜下尼氏胃底折叠术可以安全地施行,中转开腹率低且无手术死亡。神经功能受损的儿童更容易发生围手术期和术后并发症。大多数患者可以获得良好的生活质量和较高的满意度。