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神经功能受损儿童胃食管反流手术治疗的风险与益处

Risks and benefits of surgical management of gastroesophageal reflux in neurologically impaired children.

作者信息

Esposito C, Van Der Zee D C, Settimi A, Doldo P, Staiano A, Bax N M A

机构信息

Department of Experimental and Clinical Medicine, Magna Graecia University, Via Tommaso Campanella 115, 88100 Catanzaro, Italy.

出版信息

Surg Endosc. 2003 May;17(5):708-10. doi: 10.1007/s00464-002-9170-6. Epub 2003 Mar 6.

Abstract

BACKGROUND

The aim of this study was to investigate the feasibility and results of laparoscopic antireflux procedure in neurologically impaired children.

METHODS

Over a 5-yr period, 259 children affected by gastroesophageal reflux disease underwent laparoscopic antireflux procedure. Eighty of them (30.8%) were neurologically impaired. In 58 children we performed an anterior fundoplication according to Thal and in 22 patients a 360 degrees fundoplication according to Nissen. Forty-eight children underwent an associated gastrostomy placement at the same time as the laparoscopic antireflux procedure.

RESULTS

We recorded 4/80 intraoperative complications; in all cases the complication was managed laparoscopically and no conversion was needed. Follow-up ranged from 6 months to 6 yrs (median 3 yrs). We recorded 24/80 postoperative complications, 5 of which required a redo procedure. We have a mortality rate of 17.5% but in only one case was the event related to the antireflux procedure.

CONCLUSIONS

Laparoscopic fundoplication can be performed safely and with acceptable results in neurologically impaired children. The indication to add a gastrostomy should be tailored to the needs of the individual patient. Mortality rate in neurologically impaired children patients with gastroesophageal reflux disease is high but in most cases unrelated to the antireflux procedure.

摘要

背景

本研究旨在探讨腹腔镜抗反流手术在神经功能受损儿童中的可行性及效果。

方法

在5年期间,259例患有胃食管反流病的儿童接受了腹腔镜抗反流手术。其中80例(30.8%)神经功能受损。58例儿童根据塔尔法进行了前位胃底折叠术,22例患者根据nissen法进行了360度胃底折叠术。48例儿童在腹腔镜抗反流手术的同时进行了胃造口术。

结果

我们记录到4/80例术中并发症;所有病例均通过腹腔镜处理,无需中转开腹。随访时间为6个月至6年(中位时间3年)。我们记录到24/80例术后并发症,其中5例需要再次手术。我们的死亡率为17.5%,但只有1例事件与抗反流手术有关。

结论

腹腔镜胃底折叠术在神经功能受损儿童中可安全进行,且效果可接受。是否增加胃造口术应根据个体患者的需求来决定。神经功能受损的胃食管反流病儿童患者死亡率较高,但在大多数情况下与抗反流手术无关。

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