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用主动态模式对海马体非线性动态变换进行建模。

Modeling hippocampal nonlinear dynamic transformations with principal dynamic modes.

作者信息

Courellis Spiros H, Zanos Theodoros P, Hsiao Min Chi, Hampson Robert E, Deadwyler Sam A, Marmarelis Vasilis Z, Berger Theodore W

机构信息

Biomedical Engineering Department, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.

出版信息

Conf Proc IEEE Eng Med Biol Soc. 2006;2006:2300-3. doi: 10.1109/IEMBS.2006.260271.

Abstract

A new modeling approach of hippocampal nonlinear dynamics is presented. It is based on Principal Dynamics Modes (PDMs) derived from the Volterra kernels quantifying the hippocampal transformations. The approach is illustrated using data obtained from acute hippocampal slice preparations and from behaving rats performs a memory task. The resulting PDM models are comparable in performance to the Volterra models and require significantly less representational and implementational overhead.

摘要

提出了一种新的海马体非线性动力学建模方法。它基于从量化海马体变换的沃尔泰拉核导出的主动力学模式(PDM)。使用从急性海马体切片制备物以及执行记忆任务的行为大鼠获得的数据对该方法进行了说明。所得的PDM模型在性能上与沃尔泰拉模型相当,并且所需的表示和实现开销显著更少。

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