Whalen Diana J, Silk Jennifer S, Semel Mara, Forbes Erika E, Ryan Neal D, Axelson David A, Birmaher Boris, Dahl Ronald E
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
J Pediatr Psychol. 2008 May;33(4):358-67. doi: 10.1093/jpepsy/jsm086. Epub 2007 Oct 18.
Sleep problems are a cardinal symptom of depression in children and adolescents and caffeine use is a prevalent and problematic issue in youth; yet little is known about caffeine use and its effects on sleep in youth with depression. We examined caffeine use and its relation to sleep and affect in youth's natural environments.
Thirty youth with major depressive disorder (MDD) and 23 control youth reported on caffeine use, sleep, and affect in their natural environment using ecological momentary assessment at baseline and over 8 weeks, while MDD youth received treatment.
Youth with MDD reported more caffeine use and sleep problems relative to healthy youth. Youth with MDD reported more anxiety on days they consumed caffeine. Caffeine use among youth with MDD decreased across treatment, but sleep complaints remained elevated.
Findings suggest that both sleep quality and caffeine use are altered in pediatric depression; that caffeine use, but not sleep problems, improves with treatment; and that caffeine may exacerbate daily anxiety among youth with depression.
睡眠问题是儿童和青少年抑郁症的主要症状,而咖啡因的使用在青少年中是一个普遍且存在问题的现象;然而,关于抑郁症青少年的咖啡因使用情况及其对睡眠的影响却知之甚少。我们在青少年的自然环境中研究了咖啡因的使用情况及其与睡眠和情绪的关系。
30名患有重度抑郁症(MDD)的青少年和23名对照青少年在基线及8周时间内,通过生态瞬时评估法报告了他们在自然环境中的咖啡因使用情况、睡眠情况和情绪,同时MDD青少年接受治疗。
与健康青少年相比,患有MDD的青少年报告的咖啡因使用量和睡眠问题更多。患有MDD的青少年在饮用咖啡因的日子里报告有更多焦虑情绪。MDD青少年的咖啡因使用量在治疗过程中有所下降,但睡眠问题仍然较多。
研究结果表明,儿童抑郁症患者的睡眠质量和咖啡因使用情况均发生了改变;咖啡因的使用情况在治疗后有所改善,但睡眠问题没有改善;咖啡因可能会加剧抑郁症青少年的日常焦虑情绪。