Leon-Villapalos J, Wolfe K, Calonje E, Kangesu L
St Andrews Centre for Plastic Surgery, Court Road, Broomfield, Chelmsford, Essex CM1 7ET, UK.
J Plast Reconstr Aesthet Surg. 2007;60(11):1260-2. doi: 10.1016/j.bjps.2006.01.019. Epub 2006 May 11.
Solitary and multicentric myofibromas are rare fibrous tumours with marked predilection for infants and young children. Presentation is mainly before the age of 2 and lesions are often congenital. Behaviour is usually benign, but mortality has been described in lesions with visceral involvement. We report a unique case of congenital solitary cutaneous infantile myofibroma in a neonate associated with self-limiting thrombocytopaenia. It is important to distinguish accurately these lesions from benign vascular tumours like haemangiomas, locally aggressive vascular tumours like Kaposiform haemangioendotheliomas, which are often associated with Kasabach-Merritt phenomenon and also with malignant soft tissue tumours of infancy.
孤立性和多中心性肌纤维瘤是罕见的纤维性肿瘤，明显好发于婴幼儿。发病主要在2岁之前，病变常为先天性。其行为通常为良性，但有文献报道内脏受累的病变可导致死亡。我们报告了1例新生儿先天性孤立性皮肤婴儿肌纤维瘤，伴有自限性血小板减少症。准确区分这些病变与良性血管肿瘤（如血管瘤）、局部侵袭性血管肿瘤（如卡波西型血管内皮瘤，常与卡萨巴赫-梅里特现象相关，也与婴儿期恶性软组织肿瘤相关）非常重要。
