Heath Michael, Hajar Tamar, Korcheva Vessy, Leitenberger Justin
Department of Dermatology, Oregon Health and Science University, Portland, Oregon.
J Cutan Pathol. 2018 Feb;45(2):159-161. doi: 10.1111/cup.13071. Epub 2017 Dec 10.
Myofibromas are unusual benign tumors most commonly seen in infant children. Clinical involution of the tumor often occurs within the first few years of life. Solitary cutaneous myofibroma is the synonymous adult counterpart of infantile myofibromatosis. Although solitary myofibromas have been reported in patients of all ages, only the infantile variant is believed to regress spontaneously. There are only a few case reports of adolescent and young adult patients with regressing solitary lesions that have been described in the literature to date. We report a 71-year-old male with spontaneous regression of solitary cutaneous myofibroma. The residual lesion was excised and to date has not recurred. This report describes the historical, clinical and histopathological features of adult myofibromas and a novel manifestation that may guide future clinical considerations when approaching solitary tumors with regressive features.
肌纤维瘤是一种罕见的良性肿瘤，最常见于婴幼儿。肿瘤通常在生命的最初几年内发生临床消退。孤立性皮肤肌纤维瘤是婴儿肌纤维瘤病的成人对应物。虽然各年龄段患者均有孤立性肌纤维瘤的报道，但只有婴儿型变种被认为可自发消退。迄今为止，文献中仅有少数关于青少年和青年成人患者孤立性病变消退的病例报告。我们报告一例71岁男性，其孤立性皮肤肌纤维瘤自发消退。残留病变已切除，至今未复发。本报告描述了成人肌纤维瘤的历史、临床和组织病理学特征，以及一种新的表现形式，这可能为未来处理具有消退特征的孤立性肿瘤时的临床考虑提供指导。
