Yabe Ichiro, Matsushima Masaaki, Soma Hiroyuki, Basri Rehana, Sasaki Hidenao
Department of Neurology, Hokkaido Graduate School of Medicine, N15 W7 Kita-ku, Sapporo 060-8638, Japan.
J Neurol Sci. 2008 Mar 15;266(1-2):164-6. doi: 10.1016/j.jns.2007.09.021. Epub 2007 Oct 22.
In this study, we examined the usefulness and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in assessing cerebellar ataxia in 27 patients with spinocerebellar degeneration. The inter-rater reliability of the SARA scores between the two neurologists was high. The scores on SARA correlated significantly with the Barthel index and scores on the International Cooperative Ataxia Rating Scale (ICARS). Scores on ICARS and SARA did not correlate with the total length traveled (TLT) or the root mean square area (RMS) of body sways measured by body stabilometry. The time required to examine each patient for SARA was approximately 4 min, one-third the time required for ICARS. Our results indicate that SARA is useful for the evaluation of cerebellar ataxic patients in daily examinations and that body sway analysis by stabilometry is influenced by factors other than cerebellar ataxia, such as muscle weakness, which should be taken into account when body sway analysis is used to evaluate the severity of cerebellar ataxia.
在本研究中,我们检测了共济失调评估与分级量表(SARA)在评估27例脊髓小脑变性患者小脑共济失调方面的实用性和有效性。两位神经科医生之间SARA评分的评分者间信度较高。SARA评分与巴氏指数以及国际协作共济失调评级量表(ICARS)评分显著相关。ICARS和SARA评分与通过身体稳定测量法测得的身体摆动的行进总长度(TLT)或均方根面积(RMS)无关。使用SARA检查每位患者所需的时间约为4分钟,是ICARS所需时间的三分之一。我们的结果表明,SARA在日常检查中对小脑共济失调患者的评估很有用,并且通过稳定测量法进行的身体摆动分析受小脑共济失调以外的因素(如肌肉无力)影响,在使用身体摆动分析评估小脑共济失调严重程度时应予以考虑。