当今的比较肿瘤学。
Comparative oncology today.
作者信息
Paoloni Melissa C, Khanna Chand
机构信息
Comparative Oncology Program, National Cancer Institute, National Institutes of Health, 37 Convent Drive, Room 2144, Bethesda, MD 20892, USA.
出版信息
Vet Clin North Am Small Anim Pract. 2007 Nov;37(6):1023-32; v. doi: 10.1016/j.cvsm.2007.08.003.
Abstract
The value of comparative oncology has been increasingly recognized in the field of cancer research, including the identification of cancer-associated genes; the study of environmental risk factors, tumor biology, and progression; and, perhaps most importantly, the evaluation of novel cancer therapeutics. The fruits of this effort are expected to be the creation of better and more specific drugs to benefit veterinary and human patients who have cancer. The state of the comparative oncology field is outlined in this article, with an emphasis on cancer in dogs.
摘要
比较肿瘤学在癌症研究领域的价值已得到越来越多的认可，包括癌症相关基因的鉴定；环境风险因素、肿瘤生物学和进展的研究；以及，也许最重要的是，新型癌症治疗方法的评估。这项努力的成果有望是研发出更好、更具特异性的药物，以使患癌的兽医和人类患者受益。本文概述了比较肿瘤学领域的现状，重点是犬类癌症。
相似文献
1
Comparative oncology today.
Vet Clin North Am Small Anim Pract. 2007 Nov;37(6):1023-32; v. doi: 10.1016/j.cvsm.2007.08.003.
2
The role of clinical trials in veterinary oncology.
Vet Clin North Am Small Anim Pract. 2014 Sep;44(5):977-87. doi: 10.1016/j.cvsm.2014.05.006.
3
How dogs are teaching researchers new tricks for treating cancer.
Nature. 2018 Nov;563(7731):S50-S51. doi: 10.1038/d41586-018-07365-2.
4
Update on genomics in veterinary oncology.
Top Companion Anim Med. 2009 Aug;24(3):113-21. doi: 10.1053/j.tcam.2009.03.002.
5
Bringing the Genomic Revolution to Comparative Oncology: Human and Dog Cancers.
Annu Rev Biomed Data Sci. 2024 Aug;7(1):107-129. doi: 10.1146/annurev-biodatasci-102423-111936. Epub 2024 Jul 24.
6
Leveraging Comparative Oncology in the Hopes of Improving Therapies for Breast Cancer.
Semin Oncol. 2017 Aug;44(4):301. doi: 10.1053/j.seminoncol.2017.11.003. Epub 2017 Nov 23.
7
Advances in small animal oncology.
J Small Anim Pract. 2006 Sep;47(9):501-2. doi: 10.1111/j.1748-5827.2006.00219.x.
8
The changing face of cancer treatment.
J Small Anim Pract. 2003 Aug;44(8):383.
9
Evidence-based integrative medicine in clinical veterinary oncology.
Vet Clin North Am Small Anim Pract. 2014 Sep;44(5):831-53. doi: 10.1016/j.cvsm.2014.06.002.
10
Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document.
Vet Comp Oncol. 2015 Sep;13(3):176-83. doi: 10.1111/vco.12032. Epub 2013 Mar 28.
引用本文的文献
1
Building a Therapeutic Bridge Between Dogs and Humans: A Review of Potential Cross-Species Osteosarcoma Biomarkers.
Int J Mol Sci. 2025 May 28;26(11):5152. doi: 10.3390/ijms26115152.
2
Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology.
Front Mol Biosci. 2025 May 22;12:1615393. doi: 10.3389/fmolb.2025.1615393. eCollection 2025.
3
A single-cell RNA sequencing atlas of the healthy canine lung: a foundation for comparative studies.
Front Immunol. 2025 Mar 6;16:1501603. doi: 10.3389/fimmu.2025.1501603. eCollection 2025.
4
Metronomic chemotherapy: bridging theory to clinical application in canine and feline oncology.
Front Vet Sci. 2024 Jun 6;11:1397376. doi: 10.3389/fvets.2024.1397376. eCollection 2024.
5
Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology.
Vet Med Int. 2024 May 10;2024:9319651. doi: 10.1155/2024/9319651. eCollection 2024.
6
Comparative characterisation of extracellular vesicles from canine and human plasma: a necessary step in biomarker discovery.
Vet Res Commun. 2024 Aug;48(4):2775-2782. doi: 10.1007/s11259-024-10405-0. Epub 2024 May 8.
7
Comparative oncology chemosensitivity assay for personalized medicine using low-coherence digital holography of dynamic light scattering from cancer biopsies.
Sci Rep. 2024 Feb 8;14(1):2760. doi: 10.1038/s41598-024-52404-w.
8
Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics.
Sci Rep. 2023 Jul 6;13(1):10935. doi: 10.1038/s41598-023-37505-2.
9
A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma.
Mol Ther. 2023 Aug 2;31(8):2342-2359. doi: 10.1016/j.ymthe.2023.06.004. Epub 2023 Jun 12.
10
Can Chemotherapy Negatively Affect the Specific Antibody Response toward Core Vaccines in Canine Cancer Patients?
Vet Sci. 2023 Apr 20;10(4):303. doi: 10.3390/vetsci10040303.
本文引用的文献
1
Using the canine genome to cure cancer and other diseases.
Theriogenology. 2007 Aug;68(3):378-81. doi: 10.1016/j.theriogenology.2007.04.016. Epub 2007 May 10.
2
A single IGF1 allele is a major determinant of small size in dogs.
Science. 2007 Apr 6;316(5821):112-5. doi: 10.1126/science.1137045.
3
Cooperative activity of cytotoxic chemotherapy with antiangiogenic thrombospondin-I peptides, ABT-526 in pet dogs with relapsed lymphoma.
Clin Cancer Res. 2006 Dec 15;12(24):7456-64. doi: 10.1158/1078-0432.CCR-06-0110.
4
Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers.
Clin Cancer Res. 2006 Dec 15;12(24):7444-55. doi: 10.1158/1078-0432.CCR-06-0109.
5
Why is cancer drug discovery so difficult?
Nat Rev Drug Discov. 2007 Feb;6(2):115-20. doi: 10.1038/nrd2155. Epub 2006 Dec 8.
6
Diagnosis of mediastinal masses in dogs by flow cytometry.
J Vet Intern Med. 2006 Sep-Oct;20(5):1161-5. doi: 10.1892/0891-6640(2006)20[1161:dommid]2.0.co;2.
7
Classification of canine urinary bladder urothelial tumours based on the World Health Organization/International Society of Urological Pathology consensus classification.
J Comp Pathol. 2006 Nov;135(4):190-9. doi: 10.1016/j.jcpa.2006.07.002. Epub 2006 Oct 18.
8
The dog as a cancer model.
Nat Biotechnol. 2006 Sep;24(9):1065-6. doi: 10.1038/nbt0906-1065b.
9
Oncology of companion animals as a model for humans. an overview of tumor histotypes.
J Exp Clin Cancer Res. 2006 Mar;25(1):97-105.
10
Utility of polymerase chain reaction for analysis of antigen receptor rearrangement in staging and predicting prognosis in dogs with lymphoma.
J Vet Intern Med. 2006 Mar-Apr;20(2):329-34. doi: 10.1892/0891-6640(2006)20[329:uopcrf]2.0.co;2.
Zotero 插件