Cottrill C M, Jeffers-Lo J, Ousey J C, McGladdery A J, Ricketts S W, Silver M, Rossdale P D
University of Kentucky, Lexington 40536-0084.
J Reprod Fertil Suppl. 1991;44:591-601.
One hundred twenty-four horse placentas were evaluated according to gross appearance, weight and surface area. Grossly abnormal placentas were photographed, and histological sections were taken from abnormal appearing areas, and from representative areas (pregnant horn, non-pregnant horn, body and cervical pole) in both normal and abnormal placentas. Information about the resulting foals was obtained and correlations examined. Histological sections were reviewed and related to the resulting foals. Four normal fresh placentas were infused with dyes to ascertain the blood supply to various areas. Foal weight was statistically related to both allantochorionic surface area and allantochorionic weight. When normal placental surface area was divided by foal weight and related to gestational age, a statistical (P less than 0.0001 and r = 0.829) relationship emerged. Long cords were seen frequently with fetal demise. Histological abnormalities in the placenta were highly associated with fetal demise or fetal abnormalities, with only 2 normal Thoroughbred foals resulted from the 23 placentas exhibiting abnormal histology. Among the ponies, the same relationship held, with 3 normal ponies delivered from 9 abnormal placentas. Normal placentas were associated with normal offspring in most cases. Perfusion studies indicated that, in the four placentas studied, one umbilical artery supplied the cervical area and the non-pregnant horn, whereas the other supplied the pregnant horn. The body had a mixed supply from both arteries. This study evaluated the feto-placental unit in terms of normal and abnormal measurements and histology related to foal outcome. The presence of abnormal histological appearance of the placenta appeared to be more closely associated with foal abnormality than the percentage of placental area involved in the abnormal process. More information is needed before placental blood supply can be related to abnormal processes.
根据外观、重量和表面积对124个马胎盘进行了评估。对外观明显异常的胎盘进行拍照，并从异常区域以及正常和异常胎盘的代表性区域（孕角、非孕角、体部和宫颈极）采集组织学切片。获取了有关所产马驹的信息并进行相关性检查。对组织学切片进行复查并与所产马驹相关联。向4个正常新鲜胎盘注入染料以确定不同区域的血液供应。马驹体重与尿膜绒毛膜表面积和尿膜绒毛膜重量均存在统计学关联。当将正常胎盘表面积除以马驹体重并与妊娠年龄相关联时，出现了统计学关系（P小于0.0001且r = 0.829）。胎儿死亡时经常可见脐带过长。胎盘的组织学异常与胎儿死亡或胎儿异常高度相关，在23个组织学异常的胎盘中，仅产出2匹正常的纯种马驹。在小型马中，同样的关系成立，9个异常胎盘中产出3匹正常小马。在大多数情况下，正常胎盘与正常后代相关。灌注研究表明，在所研究的4个胎盘中，一条脐动脉供应宫颈区域和非孕角，而另一条供应孕角。体部由两条动脉混合供血。本研究从与马驹结局相关的正常和异常测量及组织学方面评估了胎儿 - 胎盘单位。胎盘组织学外观异常的存在似乎比异常过程中涉及的胎盘面积百分比与马驹异常的关联更为密切。在胎盘血液供应与异常过程相关联之前，还需要更多信息。
