De Clerck L S, Michielsen P P, Ramael M R, Janssens E, Van Maercke Y M, Van Marck E A, Stevens W J
Department of Immunology-Allergy-Rheumatology, University Hospital, Antwerp, Belgium.
J Rheumatol. 1991 Dec;18(12):1919-21.
We describe a 26-year-old patient with systemic lupus erythematosus and pulmonary and portal hypertension associated with the presence of anticardiolipin antibodies. Postmortem histological examination revealed the presence of recent thromboses of pulmonary and portal vessels. Our findings further support the concept of pulmonary hypertension being part of the antiphospholipid syndrome and suggest that portal hypertension due to intrahepatic portal vein thrombosis might be another manifestation of this syndrome.
我们描述了一名26岁患有系统性红斑狼疮、伴有抗心磷脂抗体的肺动脉高压和门静脉高压的患者。尸检组织学检查显示存在肺血管和门静脉近期血栓形成。我们的研究结果进一步支持了肺动脉高压是抗磷脂综合征一部分的概念，并提示肝内门静脉血栓形成所致的门静脉高压可能是该综合征的另一种表现形式。
