色氨酸代谢产物的神经毒性。
Neurotoxicity of tryptophan metabolites.
作者信息
Smith A J, Stone T W, Smith R A
机构信息
Division of Neuroscience and Biomedical Systems, Institute of Biomedical and Life Sciences, West Medical Building, University of Glasgow, Glasgow G12 8QQ, U.K.
出版信息
Biochem Soc Trans. 2007 Nov;35(Pt 5):1287-9. doi: 10.1042/BST0351287.
PMID:17956331
Abstract
The metabolism of tryptophan by the kynurenine pathway leads to the production of several neurotoxic compounds, some of which have been associated with neurological disorders. Recent investigation of some relevant compounds in this pathway has provided further evidence of their neurotoxicity.
摘要
色氨酸通过犬尿氨酸途径进行代谢会导致产生几种神经毒性化合物，其中一些已被认为与神经疾病有关。最近对该途径中一些相关化合物的研究进一步证实了它们的神经毒性。
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