环丙沙星和氧氟沙星对小鼠细胞免疫和体液免疫反应的影响

[The effects of ciprofloxacin and ofloxacin on the cellular and humoral immune response in mice].

作者信息

Usluer G, Ulak G, Erol K, Gürer F, Cingi M I, Ozdemir M, Alpan R S

机构信息

Anadolu Universitesi, Fakültesi Infeksiyon Hastaliklari Anabilim Dali.

出版信息

Mikrobiyol Bul. 1991 Oct;25(4):330-9.

Abstract

The effects of a 7 days chemotherapy with ciprofloxacin or ofloxacin on the cellular and humoral immune responses in albino mice were studied. The non-toxic doses of the drugs (10 or 30 mg/kg/day) were used. The delayed-type hypersensitivity reaction to sheep blood cells and skin biopsy were evaluated for cellular immune response. The complement fixation method was applied for the determination of the humoral immune response. Both drugs increased the cellular and humoral immune responses.

摘要

研究了环丙沙星或氧氟沙星进行7天化疗对白化病小鼠细胞免疫和体液免疫反应的影响。使用了无毒剂量的药物（10或30毫克/千克/天）。通过对绵羊血细胞的迟发型超敏反应和皮肤活检来评估细胞免疫反应。采用补体结合法测定体液免疫反应。两种药物均增强了细胞免疫和体液免疫反应。

相似文献

1

[The effects of ciprofloxacin and ofloxacin on the cellular and humoral immune response in mice].环丙沙星和氧氟沙星对小鼠细胞免疫和体液免疫反应的影响

Mikrobiyol Bul. 1991 Oct;25(4):330-9.

2

The effects of the anti-enteroviral agent PTU-23 on immune response in normal mice.

Biomed Pharmacother. 1986;40(1):33-6.

3

Effect of lactoferrin on the methotrexate-induced suppression of the cellular and humoral immune response in mice.乳铁蛋白对甲氨蝶呤诱导的小鼠细胞免疫和体液免疫反应抑制的影响。

Anticancer Res. 2004 Nov-Dec;24(6):3831-6.

4

Differential patterns of cyclosporine A-induced inhibition of humoral and cellular immune responses to sheep erythrocytes in mice.环孢素A对小鼠针对绵羊红细胞的体液免疫和细胞免疫反应抑制作用的差异模式。

Pol J Pharmacol. 2001 Sep-Oct;53(5):495-500.

5

Influence of new quinolones on normal immune capabilities.

J Chemother. 1990 Oct;2(5):300-5. doi: 10.1080/1120009x.1990.11739033.

6

Direct in vitro evidence for different susceptibilities to 4-hydroperoxycyclophosphamide of antigen-primed T cells regulating humoral and cell-mediated immune responses to sheep erythrocytes: a possible explanation for the inverse action of cyclophosphamide on humoral and cell-mediated immune responses.抗原致敏的T细胞对4-氢过氧环磷酰胺的敏感性不同，这直接为调节针对绵羊红细胞的体液免疫和细胞介导免疫反应提供了体外证据：这可能是环磷酰胺对体液免疫和细胞介导免疫反应产生相反作用的一种解释。

J Immunol. 1981 May;126(5):1717-9.

7

[Effect of anaprilin on the humoral and cellular immune response].[心得安对体液免疫和细胞免疫反应的影响]

Farmakol Toksikol. 1987 May-Jun;50(3):53-5.

8

Effects of ciprofloxacin on the humoral and cellular immune responses in Balb/c-mice.

Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Sep;262(3):396-402. doi: 10.1016/s0176-6724(86)80013-x.

9

Effects of lighting conditions and melatonin supplementation on the cellular and humoral immune responses in Japanese quail Coturnix coturnix japonica.光照条件和褪黑素补充剂对日本鹌鹑（Coturnix coturnix japonica）细胞免疫和体液免疫反应的影响

Gen Comp Endocrinol. 2000 Jul;119(1):95-104. doi: 10.1006/gcen.2000.7496.

10

[Interrelations of cellular and humoral immune response and different doses of sheep erythrocytes in mice].[小鼠体内细胞免疫和体液免疫反应与不同剂量绵羊红细胞的相互关系]

Biull Eksp Biol Med. 1991 Sep;112(9):271-3.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。