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高致病性H5N1禽流感侵入英国家禽群体的流行病学后果。

Epidemiological consequences of an incursion of highly pathogenic H5N1 avian influenza into the British poultry flock.

作者信息

Sharkey Kieran J, Bowers Roger G, Morgan Kenton L, Robinson Susan E, Christley Robert M

机构信息

Department of Mathematical Sciences, The University of Liverpool, Liverpool L69 7ZL, UK.

出版信息

Proc Biol Sci. 2008 Jan 7;275(1630):19-28. doi: 10.1098/rspb.2007.1100.

Abstract

Highly pathogenic avian influenza and in particular the H5N1 strain has resulted in the culling of millions of birds and continues to pose a threat to poultry industries worldwide. The recent outbreak of H5N1 in the UK highlights the need for detailed assessment of the consequences of an incursion and of the efficacy of control strategies. Here, we present results from a model of H5N1 propagation within the British poultry industry. We find that although the majority of randomly seeded incursions do not spread beyond the initial infected premises, there is significant potential for widespread infection. The efficacy of the European Union strategy for disease control is evaluated and our simulations emphasize the pivotal role of duck farms in spreading H5N1.

摘要

高致病性禽流感,尤其是H5N1毒株,已导致数百万只禽类被扑杀,并且继续对全球家禽业构成威胁。近期英国爆发的H5N1疫情凸显了详细评估疫情入侵后果以及控制策略有效性的必要性。在此,我们展示了一个关于H5N1在英国家禽业传播的模型所得到的结果。我们发现,尽管大多数随机播撒的疫情不会扩散到初始感染场所之外,但仍存在广泛感染的重大可能性。我们评估了欧盟疾病控制策略的有效性,并且我们的模拟结果强调了鸭场在传播H5N1方面的关键作用。

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