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Can inhaled prostacyclin stimulate surfactant in ELBW infants?

作者信息

Olmsted K, Oluola O, Parthiban A, Raghuveer T

机构信息

Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA.

出版信息

J Perinatol. 2007 Nov;27(11):724-6. doi: 10.1038/sj.jp.7211811.

DOI:10.1038/sj.jp.7211811
PMID:17960144
Abstract

Respiratory distress syndrome (RDS) causes significant hypoxia in extremely low birth weight (ELBW) infants. We report an ELBW infant with RDS and pulmonary hypertension whose hypoxia did not respond to inhaled nitric oxide but improved with inhaled prostacyclin. We propose that inhaled prostacyclin alleviated the hypoxia by stimulating surfactant secretion.

摘要

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