Suppr超能文献

[额部纤维性秃发的诊断与治疗评估]

[Diagnostic and therapeutic assessment of frontal fibrosing alopecia].

作者信息

Moreno-Ramírez D, Ferrándiz L, Camacho F M

机构信息

Departamento de Dermatología Médico-Quirúrgica y Venereología. Hospital Universitario Virgen Macarena. Sevilla. España.

出版信息

Actas Dermosifiliogr. 2007 Nov;98(9):594-602.

Abstract

Frontal fibrosing alopecia is a clinical entity characterized by recession of the frontotemporal hairline in middle-aged and older women. Since it was first described in 1994, more than 100 cases have been reported describing other clinical manifestations such as eyebrow and axillary alopecia, and perifollicular inflammation that help in the diagnosis of the disease and the differential diagnosis with other scarring alopecias. Histopathology reveals an inflammatory infiltrate and perifollicular lamellar fibrosis. Although numerous therapeutic options have been tested, including corticosteroids, finasteride, and minoxidil, none have shown clear benefits in terms of halting the progression of the alopecia.

摘要

额部纤维性秃发是一种临床病症,其特征为中老年女性额颞部发际线后移。自1994年首次被描述以来,已有100多例报告描述了其他临床表现,如眉毛和腋毛脱落以及毛囊周围炎症,这些有助于该疾病的诊断以及与其他瘢痕性秃发的鉴别诊断。组织病理学显示有炎性浸润和毛囊周围板层纤维化。尽管已经测试了多种治疗方法,包括皮质类固醇、非那雄胺和米诺地尔,但在阻止脱发进展方面均未显示出明显疗效。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验