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老年患者的头发老化与毛发疾病

Hair Aging and Hair Disorders in Elderly Patients.

作者信息

Villani Alessia, Ferrillo Maria, Fabbrocini Gabriella, Ocampo-Garza Sonia Sofía, Scalvenzi Massimiliano, Ruggiero Angelo

机构信息

Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

Department of Dermatology, University Hospital "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Mexico.

出版信息

Int J Trichology. 2022 Nov-Dec;14(6):191-196. doi: 10.4103/ijt.ijt_90_21. Epub 2023 Jan 31.

DOI:10.4103/ijt.ijt_90_21
PMID:37034552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10075351/
Abstract

Hair loss in elderly patients is a common complaint. It can be related to different conditions that affect patients' quality of life and represents a challenge for dermatologists. It affects both men and women during the aging process with an estimated percentage of balding after 65 years of age of 53% and 37%, respectively. Androgenetic alopecia, frontal fibrosing alopecia, senile alopecia, and erosive pustular dermatosis of the scalp are the hair diseases most frequently described in this age group. The objective of this review is to summarize the current knowledge about alopecia affecting elderly patients, differentiating between chronological hair aging signs and pathological changes, to help clinicians, offer an adequate management of these disorders to their patients.

摘要

老年患者脱发是一种常见的主诉。它可能与影响患者生活质量的不同病症相关,对皮肤科医生来说是一项挑战。在衰老过程中,男性和女性都会受到影响,据估计65岁以后秃顶的比例分别为53%和37%。雄激素性脱发、额部纤维性脱发、老年性脱发和头皮糜烂性脓疱性皮肤病是该年龄组中最常描述的毛发疾病。本综述的目的是总结目前关于影响老年患者脱发的知识,区分按年龄增长的毛发老化迹象和病理变化,以帮助临床医生为患者提供对这些病症的适当管理。

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Hair Aging and Hair Disorders in Elderly Patients.老年患者的头发老化与毛发疾病
Int J Trichology. 2022 Nov-Dec;14(6):191-196. doi: 10.4103/ijt.ijt_90_21. Epub 2023 Jan 31.
2
Hair loss in elderly women.老年女性脱发。
Eur J Dermatol. 2010 Mar-Apr;20(2):145-51. doi: 10.1684/ejd.2010.0828. Epub 2010 Feb 19.
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Hair and nail diseases in the mature patient.成年患者的毛发和指甲疾病
Clin Dermatol. 2018 Mar-Apr;36(2):159-166. doi: 10.1016/j.clindermatol.2017.10.007. Epub 2017 Oct 3.
4
Frontal Fibrosing Alopecia Mimicking Alopecia Syphilitica.酷似梅毒性脱发的额部纤维性脱发
Cureus. 2022 Feb 4;14(2):e21901. doi: 10.7759/cureus.21901. eCollection 2022 Feb.
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A multicenter descriptive analysis of 270 men with frontal fibrosing alopecia and lichen planopilaris in the United States.一项针对美国270名患有额部纤维性脱发和平顶苔藓样糠疹男性患者的多中心描述性分析。
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The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia.人类毛囊的生物学与基因组学:聚焦雄激素性脱发
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J Clin Med. 2025 Mar 11;14(6):1894. doi: 10.3390/jcm14061894.
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The exposome impact on hair health: non-pharmacological management. Part II.暴露组对头发健康的影响:非药物管理。第二部分。
An Bras Dermatol. 2025 Mar-Apr;100(2):322-327. doi: 10.1016/j.abd.2024.08.006. Epub 2025 Jan 14.
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The exposome impact on hair health: etiology, pathogenesis and clinical features ‒ Part I.暴露组对头发健康的影响:病因、发病机制及临床特征——第一部分
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本文引用的文献

1
Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose.口服米诺地尔治疗毛发疾病的综述:寻找最佳剂量
J Eur Acad Dermatol Venereol. 2021 Jul;35(7):1485-1492. doi: 10.1111/jdv.17216. Epub 2021 Mar 23.
2
Erosive pustular dermatosis of the scalp: causes and treatments.头皮侵蚀性脓疱性皮炎:病因与治疗。
Int J Dermatol. 2021 Jan;60(1):25-32. doi: 10.1111/ijd.14955. Epub 2020 Jun 9.
3
Female Androgenetic Alopecia: An Update on Diagnosis and Management.女性雄激素性脱发:诊断与治疗的最新进展。
Am J Clin Dermatol. 2020 Feb;21(1):69-84. doi: 10.1007/s40257-019-00479-x.
4
Retrospective Analysis of Skin Toxicity in Patients under Anti-EGFR Tyrosine Kinase Inhibitors: Our Experience in Lung Cancer.抗表皮生长因子受体酪氨酸激酶抑制剂治疗患者皮肤毒性的回顾性分析:我们在肺癌治疗中的经验
Open Access Maced J Med Sci. 2019 Mar 27;7(6):973-977. doi: 10.3889/oamjms.2019.170. eCollection 2019 Mar 30.
5
Characterizing hair loss in the elderly: an observational study of 163 patients.老年人脱发特征:一项对163例患者的观察性研究。
J Eur Acad Dermatol Venereol. 2019 May;33(5):e226-e228. doi: 10.1111/jdv.15462. Epub 2019 Mar 3.
6
A Comment on the Science of Hair Aging.关于毛发衰老科学的评论。
Int J Trichology. 2018 Nov-Dec;10(6):245-254. doi: 10.4103/ijt.ijt_56_18.
7
Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment.额部纤维性脱发:发病机制、诊断和治疗的最新进展。
Am J Clin Dermatol. 2019 Jun;20(3):379-390. doi: 10.1007/s40257-019-00424-y.
8
Steroid-induced changes noted on trichoscopy of patients with frontal fibrosing alopecia.在额部纤维性脱发患者的毛发镜检查中观察到的类固醇诱导变化。
J Am Acad Dermatol. 2018 Nov;79(5):956-957. doi: 10.1016/j.jaad.2018.05.001. Epub 2018 May 5.
9
Endocrine Therapy-Induced Alopecia in Patients With Breast Cancer.乳腺癌患者内分泌治疗所致脱发。
JAMA Dermatol. 2018 Jun 1;154(6):670-675. doi: 10.1001/jamadermatol.2018.0454.
10
Hair and nail diseases in the mature patient.成年患者的毛发和指甲疾病
Clin Dermatol. 2018 Mar-Apr;36(2):159-166. doi: 10.1016/j.clindermatol.2017.10.007. Epub 2017 Oct 3.