Kumar Rajesh, Gupta Arvind K, Kaushik Mahabir P
Process Technology Development Division, Defence R and D Establishment, Jhansi Road, Gwalior-474002 (MP), India.
Molecules. 2007 Aug 2;12(8):1632-40. doi: 10.3390/12081632.
A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed. The reaction involves the condensation of substituted alpha-ketooxime and N,N-dialkylaminophenylphosphonohydrazides or O-alkylphenylphosphonohydrazides and gave the corresponding phosphonohydrazido oximes in excellent yields under mild conditions.