Sarkar Rupak K, Cooley Sharon M, Donnelly Jennifer C, Walsh Thomas, Collins Claire, Geary Michael P
Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin, Ireland.
J Matern Fetal Neonatal Med. 2007 Dec;20(12):879-83. doi: 10.1080/14767050701713090.
To determine the incidence and impact of increased body mass index (BMI) on maternal and fetal morbidity in the low-risk primigravid population.
This was a prospective study with retrospective analysis of delivery outcome data. All low-risk primigravida who met the inclusion criteria during the recruitment period were approached. BMI was calculated using the formula weight/height squared. The participants were divided into five categories: 'underweight' (BMI <20 kg/m2), 'normal' (BMI 20.01-25 kg/m2), 'overweight' (BMI 25.01-30 kg/m2), 'obese' (BMI 30.01-40 kg/m2), and 'morbidly obese' (BMI >40 kg/m2). Maternal outcomes evaluated included gestation at delivery, onset of labor (spontaneous/induced/elective cesarean section), length of labor, use of oxytocin and epidural, mode of delivery, and estimated blood loss. Perinatal outcome measures included infant birth weight (kg) and centile, gestational age, ponderal index, Apgar score <7 at 5 minutes, cord pH <7.1, presence of meconium grade 3 at delivery, degree of resuscitation required, admission to neonatal intensive care unit (NICU), and duration of stay.
One thousand and eleven women participated in the study. Complete outcome data were available for 833 women (82%). A significant difference was identified in gestation at delivery between the subgroups (p < 0.004). A significant positive correlation was identified between cesarean section rates with increasing BMI, even when gestation was controlled for (p = 0.004). Similarly, women in the normal BMI group remained significantly less likely to have an infant requiring NICU admission than obese women (2.2% vs. 8.6%; p = 0.011).
High BMI is associated with longer gestations, higher operative delivery rates, and an increased rate of neonatal intensive care admission
确定体重指数(BMI)升高在低风险初产妇人群中对孕产妇和胎儿发病情况的发生率及影响。
这是一项对分娩结局数据进行回顾性分析的前瞻性研究。研究纳入了招募期间所有符合纳入标准的低风险初产妇。BMI通过体重/身高的平方公式计算得出。参与者被分为五类:“体重过轻”(BMI<20kg/m²)、“正常”(BMI 20.01 - 25kg/m²)、“超重”(BMI 25.01 - 30kg/m²)、“肥胖”(BMI 30.01 - 40kg/m²)和“病态肥胖”(BMI>40kg/m²)。评估的孕产妇结局包括分娩孕周、分娩发动情况(自然分娩/引产/择期剖宫产)、产程长度、缩宫素和硬膜外麻醉的使用情况、分娩方式以及估计失血量。围产期结局指标包括婴儿出生体重(kg)及百分位数、孕周、 ponderal指数、5分钟时阿氏评分<7分、脐动脉血pH<7.1、分娩时Ⅲ度胎粪污染情况、所需复苏程度、入住新生儿重症监护病房(NICU)以及住院时间。
1011名女性参与了本研究。833名女性(82%)有完整的结局数据。各亚组间分娩孕周存在显著差异(p<0.004)。即便对孕周进行控制,剖宫产率与BMI升高之间仍存在显著正相关(p = 0.004)。同样,BMI正常组的女性相比肥胖女性,其婴儿入住NICU的可能性显著更低(2.2%对8.6%;p = 0.011)。
高BMI与更长孕周、更高的手术分娩率以及新生儿重症监护入住率增加相关