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丘脑在围手术期神经认知障碍中的作用。

The Thalamus in Perioperative Neurocognitive Disorders.

机构信息

Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany.

Department of Neurology, National Taiwan University Hospital, Taipei City, 100225, Taiwan.

出版信息

Neuropsychol Rev. 2024 Sep;34(3):850-859. doi: 10.1007/s11065-023-09615-1. Epub 2023 Sep 22.

DOI:10.1007/s11065-023-09615-1
PMID:37736862
Abstract

Thalamus function and structure are known predictors of individual differences in the risk of age-related neurocognitive disorders (NCD), such as dementia. However, to date, little is known about their role in the perioperative setting. Here, we provide a narrative review of brain-imaging studies of preoperative and postoperative thalamus scanning parameters associated with risks of developing perioperative NCD, such as postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) during the postoperative phase. These findings are discussed in light of the concept of reserve capacity.

摘要

丘脑的功能和结构是个体发生与年龄相关的神经认知障碍(NCD),如痴呆的风险的已知预测因子。然而,迄今为止,对于它们在围手术期环境中的作用知之甚少。在这里,我们提供了一篇关于术前和术后丘脑扫描参数与围手术期 NCD 风险相关的脑成像研究的叙述性综述,例如术后谵妄(POD)和术后认知功能障碍(POCD)在术后阶段。这些发现是根据储备能力的概念来讨论的。

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本文引用的文献

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Geometric constraints on human brain function.人类大脑功能的几何约束。
Nature. 2023 Jun;618(7965):566-574. doi: 10.1038/s41586-023-06098-1. Epub 2023 May 31.
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The impact of the human thalamus on brain-wide information processing.人类丘脑对全脑信息处理的影响。
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