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伴有肝外表现的慢性丙型肝炎

Chronic hepatitis C with extrahepatic manifestations.

作者信息

Poantă Laura, Albu Adriana

机构信息

Department of Semiology, Iuliu Haţieganu University of Medicine, Cluj-Napoca.

出版信息

Rom J Intern Med. 2007;45(1):85-8.

Abstract

Chronic hepatitis C is often asymptomatic and is mostly discovered accidentally. The natural course of viral C infection varies considerably from one person to another. Chronic hepatitis C more than other forms of hepatitis is diagnosed because of extrahepatic manifestations associated with the presence of HCV such as thyroiditis, porphyria cutanea tarda, cryoglobulinemia and glomerulonephritis, specifically membranoproliferative glomerulonephritis, sicca syndrome, thrombocytopenia, lichen planus, diabetes mellitus and B-cell lymphoproliferative disorders. We report here a case of a young man with hepatitis C and porphyria cutanea tarda who developed psoriasis after the beginning of systemic interferon therapy.

摘要

慢性丙型肝炎通常没有症状,大多是偶然发现的。丙型病毒感染的自然病程在个体之间差异很大。与其他形式的肝炎相比,慢性丙型肝炎更多是由于与丙型肝炎病毒(HCV)存在相关的肝外表现而被诊断出来的,这些表现包括甲状腺炎、迟发性皮肤卟啉症、冷球蛋白血症和肾小球肾炎,特别是膜增生性肾小球肾炎、干燥综合征、血小板减少症、扁平苔藓、糖尿病和B细胞淋巴增殖性疾病。我们在此报告一例患有丙型肝炎和迟发性皮肤卟啉症的年轻男子,在开始全身干扰素治疗后出现了银屑病。

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