Ibrahim El-Sayed H, Stuber Matthias, Fahmy Ahmed S, Abd-Elmoniem Khaled Z, Sasano Tetsuo, Abraham M Roselle, Osman Nael F
Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21287, USA.
J Magn Reson Imaging. 2007 Dec;26(6):1461-70. doi: 10.1002/jmri.21125.
To implement real-time myocardial strain-encoding (SENC) imaging in combination with tracking the tissue displacement in the through-plane direction.
SENC imaging was combined with the slice-following technique by implementing three-dimensional (3D) selective excitation. Certain adjustments were implemented to reduce scan time to one heartbeat. A total of 10 volunteers and five pigs were scanned on a 3T MRI scanner. Spatial modulation of magnetization (SPAMM)-tagged images were acquired on planes orthogonal to the SENC planes for comparison. Myocardial infarction (MI) was induced in two pigs and the resulting SENC images were compared to standard delayed-enhancement (DE) images.
The strain values computed from SENC imaging with slice-following showed significant difference from those acquired without slice-following, especially during systole (P < 0.01). The strain curves computed from the SENC images with and without slice-following were similar to those computed from the orthogonal SPAMM images, with and without, respectively, tracking the tag line displacement in the strain direction. The resulting SENC images showed good agreement with the DE images in identifying MI in infarcted pigs.
Correction of through-plane motion in real-time cardiac functional imaging is feasible using slice-following. The strain measurements are more accurate than conventional SENC measurements in humans and animals, as validated with conventional MRI tagging.
实现实时心肌应变编码（SENC）成像，并结合跟踪平面内方向的组织位移。
通过实施三维（3D）选择性激发，将SENC成像与切片跟踪技术相结合。进行了某些调整以将扫描时间缩短至一个心跳周期。在3T MRI扫描仪上对总共10名志愿者和5头猪进行了扫描。在与SENC平面正交的平面上采集了磁化空间调制（SPAMM）标记图像以进行比较。在2头猪中诱导心肌梗死（MI），并将所得的SENC图像与标准延迟增强（DE）图像进行比较。
通过切片跟踪的SENC成像计算得到的应变值与未进行切片跟踪时获得的应变值有显著差异，尤其是在收缩期（P < 0.01）。有无切片跟踪的SENC图像计算得到的应变曲线分别与有无在应变方向跟踪标记线位移的正交SPAMM图像计算得到的应变曲线相似。所得的SENC图像在识别梗死猪的MI方面与DE图像显示出良好的一致性。
使用切片跟踪在实时心脏功能成像中校正平面内运动是可行的。如通过传统MRI标记所验证的，应变测量在人和动物中比传统SENC测量更准确。
Zotero 插件