聚（ADP - 核糖）聚合酶：分子生物学方面
Poly(ADP-ribose) polymerase: molecular biological aspects.
作者信息
de Murcia G, Ménissier-de Murcia J, Schreiber V
机构信息
Institut de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, Strasbourg, France.
出版信息
Bioessays. 1991 Sep;13(9):455-62. doi: 10.1002/bies.950130905.
PMID:1796908
Abstract
A number of roles have been ascribed to poly(ADP-ribose) polymerase* including involvement in DNA repair, cell proliferation, differentiation and transformation. Cloning of the gene has allowed the development of molecular biological approaches to elucidate the structure and the function(s) of this highly conserved enzyme. This article will review the recent results obtained in this field.
摘要
聚（ADP - 核糖）聚合酶*具有多种作用，包括参与DNA修复、细胞增殖、分化和转化。该基因的克隆使得能够开发分子生物学方法来阐明这种高度保守酶的结构和功能。本文将综述该领域最近取得的成果。
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