Carvajal-Balaguera J, García-Almenta M Martín, Oliart Delgado de Torres S, Camuñias-Segovia J, Peña-Gamarra L, Fernández I P, Gómez-Maestro P, Prieto Sánchez A, Viso-Ciudad S, Cerquella-Hernández C Ma
Servicio de Cirugía General y Digestiva, Hospital Central de la Cruz Roja San José y Santa Adela de Madrid, España.
Nutr Hosp. 2007 Sep-Oct;22(5):607-11.
Gastric Bypass (GB) constitutes the surgical treatment of election of morbid obesity (BMI < 50) at the present time, however doubts exist about its effectiveness in super obesity patients (BMI > 50).
The purpose of this work is one of to analyze the results of loss of weight of the first 52 open GB of our series, and to compare the losses of weight in morbid obesity (MO) and super obesity (SO), to determine if the superobese patient looses enough weight with this technique or if it would be more indicated another technique more malabsorptive, like some authors recommend.
Retrospective study of the first 52 patients operated of open GB pathway. The weight loss of 32 patients' with MO are compared with the weight loss of 20 patients with super obesity after five year follow-up. The parameters analyzed are: age, sex, height, initial weight, current weight, initial BMI, current BMI, % BMI lost, % overweight lost, incidence of incisional hernia, acceptable oral tolerance and metabolic alterations. The malabsorptive procedure associated in patients with super obesity was a 200 cm Roux-en-Y and a patients with BMI between 40 and 50 was a 150 cm Roux-en-Y. The results are compared by means of the X2 and Mann Whitney statistical test.
The age, the sex and the stature are homogeneous in the two groups. In the group of MO the initial weight was of 121.5 kg; initial BMI, 45; current BMI; 28.9, the median loss of weight in 5 years was of 48 kg; the percentage loss of the excess of BMI is of 80% and the percentage loss of the excess of weight is of 74.6%. In the group of SO the initial weight was of 142.,7 kg; initial BMI, 54.9; current BMI, 34.,9; the median loss of weight in 5 years was of 54 kg; the percentage loss of the excess of BMI was of 65,3% and the percentage loss of the excess of weight was of 63.2%. The analysis of the results ponders shows that it exists statistically significant differences (P < 0.05) among the two groups, however the rate of success, according to the classic parameter of loss of more than 50% of the excess of weight, was superior to 90% in both groups. The results of the study about the presence of incisional postoperative hernia, alimentary tolerance and metabolic alterations, indicate that it doesn't exist differences statistically significant between both groups.
GB is an effective surgical technique in patients with morbid obesity and with super obesity, provided that in these patients is realized a procedure more malabsorptive. There are not differences between both groups, in morbidity, improvement in the associate disease, alimentary tolerance and necessity of nutritional supplements.
胃旁路手术(GB)是目前治疗病态肥胖(BMI < 50)的首选手术方式,但对于超级肥胖患者(BMI > 50)其有效性仍存在疑问。
本研究旨在分析我们系列中首批52例开放式GB手术的体重减轻结果,比较病态肥胖(MO)和超级肥胖(SO)患者的体重减轻情况,以确定超级肥胖患者采用该技术是否能减轻足够体重,或者是否如一些作者所建议的那样,采用更具吸收不良性的其他技术会更合适。
对首批52例行开放式GB手术的患者进行回顾性研究。对32例MO患者和20例超级肥胖患者进行了五年随访后的体重减轻情况进行比较。分析的参数包括:年龄、性别、身高、初始体重、当前体重、初始BMI、当前BMI、BMI降低百分比、超重降低百分比、切口疝发生率、可接受的口服耐受性和代谢改变。超级肥胖患者采用的吸收不良手术方式为200cm Roux - en - Y,BMI在40至50之间的患者采用的是150cm Roux - en - Y。通过X2检验和曼 - 惠特尼统计检验对结果进行比较。
两组患者的年龄、性别和身高具有同质性。MO组初始体重为121.5kg;初始BMI为45;当前BMI为28.9,5年体重减轻中位数为48kg;BMI超重部分降低百分比为80%,体重超重部分降低百分比为74.6%。SO组初始体重为142.7kg;初始BMI为54.9;当前BMI为34.9;5年体重减轻中位数为54kg;BMI超重部分降低百分比为65.3%,体重超重部分降低百分比为63.2%。对结果的分析表明两组之间存在统计学显著差异(P < 0.05),然而,根据体重超重部分降低超过50%这一经典参数,两组的成功率均超过90%。关于术后切口疝、饮食耐受性和代谢改变的研究结果表明两组之间不存在统计学显著差异。
GB是治疗病态肥胖和超级肥胖患者的有效手术技术,前提是在这些患者中实施更具吸收不良性的手术。两组在发病率、相关疾病改善情况、饮食耐受性和营养补充需求方面没有差异。