Smilković P, Ocić G, Filipović S, Lević Z, Drulović J
Srp Arh Celok Lek. 1994 Jan-Feb;122(1-2):19-21.
Neuropsychological investigation of 25 patients with multiple sclerosis was carried out. The aim of the study was the detection of vulnerability of certain neuropsychological functions caused by demyelinating process and estimation of impact of the clinical characteristics of the disease on cognitive functioning. Neuropsychological evaluation was performed by Luria-Nebraska Neuropsychological Battery. The analysis of the Clinical and Factor Scales results revealed that attention, memory and intellectual functions were the most disturbed. In comparison with the achievements of the control group, the group of non-demented patients with multiple sclerosis scored lower on all Clinical Scales. The results of the present neuropsychological examination pointed out that the impairment of neuropsychological functions in patients with multiple sclerosis comprised the two levels of functioning. The first, that was more dependent on neurological deficit and the second, that included mental plan of functioning. The statistical analysis did not reveal significant correlation between neuropsychological achievements and the form and duration of illness.
对25例多发性硬化症患者进行了神经心理学调查。该研究的目的是检测脱髓鞘过程导致的某些神经心理功能的易损性，并评估疾病临床特征对认知功能的影响。采用鲁利亚-内布拉斯加神经心理成套测验进行神经心理学评估。对临床量表和因子量表结果的分析表明，注意力、记忆力和智力功能受干扰最严重。与对照组的成绩相比，非痴呆型多发性硬化症患者组在所有临床量表上的得分都较低。本次神经心理学检查结果指出，多发性硬化症患者神经心理功能损害包括两个功能水平。第一个水平更多地依赖于神经功能缺损，第二个水平包括功能的心理计划。统计分析未显示神经心理学成绩与疾病形式和病程之间存在显著相关性。
