Matsumoto Takayuki, Iwao Yasushi, Igarashi Masahiro, Watanabe Kenji, Otsuka Kazuo, Watanabe Toshiaki, Iizuka Bunei, Hida Nobuyuki, Sada Miwa, Chiba Toshimi, Kudo Shin-Ei, Oshitani Nobuhide, Nagawa Hirokazu, Ajioka Yoichi, Hibi Toshifumi
Department of Lower Gastroenterology, Hyogo College of Medicine, Nishinomiya, Japan.
Inflamm Bowel Dis. 2008 Feb;14(2):259-64. doi: 10.1002/ibd.20267.
Clinical and epidemiological studies have revealed that the incidence of colorectal cancer associated with ulcerative colitis increases with long-term chronic inflammation. Careful endoscopic observation and histological studies to check for dysplasia in the colon are important in detecting neoplasia. Current surveillance protocols mainly involve frequent step biopsies to yield a reasonable rate of dysplasia detection. However, recent studies using chromoendoscopy or magnifying endoscopy have proposed that neoplastic changes may be detected efficiently. Therefore, it is very important to understand the typical endoscopic findings found in neoplastic changes in patients proven to have long-standing ulcerative colitis. In this review, we demonstrate the typical endoscopic findings by conventional endoscopy and chromoendoscopy.
临床和流行病学研究表明，溃疡性结肠炎相关的结直肠癌发病率会随着长期慢性炎症而增加。仔细的内镜观察以及检查结肠发育异常的组织学研究对于检测肿瘤形成很重要。目前的监测方案主要包括频繁的分步活检，以获得合理的发育异常检出率。然而，最近使用染色内镜或放大内镜的研究表明，可以有效地检测到肿瘤性变化。因此，了解经证实患有长期溃疡性结肠炎患者肿瘤性变化中的典型内镜表现非常重要。在本综述中，我们展示了传统内镜和染色内镜下的典型内镜表现。
