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[白塞病]

[Behcet's disease].

作者信息

Bogić M, Rasković S, Sojić J, Milićević B

出版信息

Srp Arh Celok Lek. 1995 Sep-Oct;123(9-10):261-5.

Abstract

Behcet's disease is a recurrent, systemic inflammatory disease of the vasculitides group. It has been most frequently diagnosed in Japan and east Mediterranean countries. Its clinical picture is characterised by multiple organ and systemic defects indicating vasculitis. In addition to triple symptom of complex (recurrent ulcerations of the oral cavity and genital organs, eye lesions in the form of episcleritis, uveitis and hypopyon), other symptoms and signs are also frequent. Aetiology of the disease has not yet been completely elucidated. Immunosuprressive agents, as a single therapy or combined with glycocorticoid drugs, are used in treatment of Behcet's disease. As for the prognosis of the Behcet's disease, chronic exacerbation of the symptoms and signs is typical, and insufficiently aggressively treated posterior uveitis usually results in blindness. The prognosis is also poor in case of central nervous system and large arterial blood vessels lesions.

摘要

白塞病是一种复发性全身性血管炎性疾病。在日本和东地中海国家的诊断最为常见。其临床表现的特征是多器官和全身性损害,提示血管炎。除了三联征(口腔和生殖器反复溃疡、以巩膜外层炎、葡萄膜炎和前房积脓形式出现的眼部病变)外,其他症状和体征也很常见。该病的病因尚未完全阐明。免疫抑制剂作为单一疗法或与糖皮质激素类药物联合使用,用于治疗白塞病。至于白塞病的预后,症状和体征的慢性加重很典型,后葡萄膜炎若治疗不够积极通常会导致失明。中枢神经系统和大动脉血管病变的预后也很差。

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