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休闲时间的体育活动而非职业体育活动,对成年人群的心血管危险因素有显著影响。

Leisure time but not occupational physical activity significantly affects cardiovascular risk factors in an adult population.

作者信息

Sofi F, Capalbo A, Marcucci R, Gori A M, Fedi S, Macchi C, Casini A, Surrenti C, Abbate R, Gensini G F

机构信息

Thrombosis Centre, University of Florence, and Azienda Ospedaliero-Universitaria Careggi, Italy.

出版信息

Eur J Clin Invest. 2007 Dec;37(12):947-53. doi: 10.1111/j.1365-2362.2007.01884.x. Epub 2007 Nov 1.

Abstract

BACKGROUND

A large number of studies have demonstrated that regular physical activity during leisure time (LTPA) accounts for a significant protection against cardiovascular diseases (CVD). On the other hand, conflicting findings on the beneficial effects of occupational physical activity (OPA) have been reported. The aim of this study is to evaluate the possible influence of different amounts of LTPA and OPA on circulating levels of several parameters associated with an increased risk of CVD.

MATERIALS AND METHODS

We studied 932 individuals (365 M; 567 F, with a mean age of 54 years) living in Florence, Italy, who were enrolled in a population study conducted between 2002 and 2004. Subjects were divided into three classes of LTPA and OPA according to a score derived from a questionnaire that assessed the amount of physical activity performed.

RESULTS

LTPA was inversely related to body mass index (BMI), hip circumference, diastolic blood pressure and triglycerides, as well as directly correlated with high-density lipoprotein (HDL) cholesterol. Likewise, a higher OPA was found to be associated with higher HDL cholesterol levels. Moreover, a multivariate logistical regression analysis, adjusted for possible confounders, showed that a moderate-to-high intensity of LTPA was able to confer a significant protection against having abnormal levels of BMI, waist circumference and triglycerides, main features of the metabolic syndrome, whereas no associations between these parameters and OPA were observed.

CONCLUSIONS

A moderate-to-high LTPA was found to be significantly associated with a more favourable cardiovascular risk profile in terms of anthropometric, metabolic and lipid parameters among an Italian population. In addition, a relationship between OPA and HDL-cholesterol was reported.

摘要

背景

大量研究表明,休闲时间进行规律的体育活动(LTPA)对心血管疾病(CVD)具有显著的预防作用。另一方面,关于职业体育活动(OPA)有益影响的研究结果却相互矛盾。本研究的目的是评估不同量的LTPA和OPA对与CVD风险增加相关的几个参数循环水平的可能影响。

材料与方法

我们研究了居住在意大利佛罗伦萨的932名个体(365名男性;567名女性,平均年龄54岁),他们参与了2002年至2004年进行的一项人群研究。根据一份评估体育活动量的问卷得出的分数,将受试者分为LTPA和OPA的三个等级。

结果

LTPA与体重指数(BMI)、臀围、舒张压和甘油三酯呈负相关,与高密度脂蛋白(HDL)胆固醇呈正相关。同样,较高的OPA与较高的HDL胆固醇水平相关。此外,在对可能的混杂因素进行调整的多变量逻辑回归分析中,发现中高强度的LTPA能够显著预防BMI、腰围和甘油三酯异常,这些是代谢综合征的主要特征,而未观察到这些参数与OPA之间的关联。

结论

在意大利人群中,发现中高强度的LTPA在人体测量、代谢和脂质参数方面与更有利的心血管风险状况显著相关。此外,还报告了OPA与HDL胆固醇之间的关系。

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