Heffner Alan C, Johnson David P
Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
J Emerg Med. 2008 Nov;35(4):385-7. doi: 10.1016/j.jemermed.2007.04.013. Epub 2007 Sep 17.
A 35-year-old postpartum lactating woman presented with dyspnea and was found to be in non-diabetic ketoacidosis (pH 7.24, HCO3 10 mmol/L, urine ketones>80 mg/dL). Rapid clinical and laboratory resolution occurred after intravenous dextrose and enteral feeding along with discontinuation of lactation. This represents a rarely reported case of lactation "bovine" ketoacidosis in humans. We review the historical precedence for the diagnosis and detail the underlying physiology.
一名35岁的产后哺乳期妇女出现呼吸困难,被发现处于非糖尿病性酮症酸中毒状态(pH 7.24,碳酸氢根10 mmol/L,尿酮>80 mg/dL)。静脉输注葡萄糖、肠内喂养并停止哺乳后,临床症状和实验室检查结果迅速得到缓解。这是一例人类罕见的哺乳期“牛型”酮症酸中毒病例。我们回顾了该诊断的历史先例,并详细阐述了潜在的生理机制。