Nikolova Rossitza, Demers Louise, Béland François
Research Center, Montreal Geriatric University Institute, 4565 Queen Mary, Montreal, Quebec, H3W 1W5 Canada.
Arch Gerontol Geriatr. 2009 Jan-Feb;48(1):28-34. doi: 10.1016/j.archger.2007.09.007. Epub 2007 Nov 5.
This study investigates the implications of different levels of cognitive decline on functional status in frail older adults. Four cognitive trajectories, including two with catastrophic cognitive decline, were defined in a 3-year study. Participants with complete cognitive and functional status data at baseline, 12 and 36 months of follow-up were included in the study (n=456). Data were analysed with repeated measures statistics. Substantial functional deterioration over time was observed for the participants with catastrophic cognitive decline. Catastrophic cognitive decline influenced performance in instrumental activities of daily living (IADL) and activities of daily living (ADL) at 12 months, whereas basic physical and mental actions were affected at 36 months. IADL were found to deteriorate more than ADL. The results have implications on planning appropriate geriatric rehabilitation and long-term care program.
本研究调查了认知能力不同程度下降对体弱老年人功能状态的影响。在一项为期3年的研究中定义了四种认知轨迹，其中包括两种具有灾难性认知下降的轨迹。研究纳入了在基线、随访12个月和36个月时具有完整认知和功能状态数据的参与者（n = 456）。采用重复测量统计方法对数据进行分析。观察到具有灾难性认知下降的参与者随着时间的推移功能显著恶化。灾难性认知下降在12个月时影响日常生活工具性活动（IADL）和日常生活活动（ADL）的表现，而在36个月时基本身体和精神活动受到影响。发现IADL的恶化程度超过ADL。这些结果对规划适当的老年康复和长期护理计划具有启示意义。
