Kwon Jin-Won, Song Yun-mi, Park Hye soon, Sung Joohon, Kim Ho, Cho Sung-il
Department of Epidemiology, School of Public Health and Institute of Health and Environment, Seoul National University, Chogno-gu Yeongun-dong 28, Seoul 110-460, Republic of Korea.
Diabetes Care. 2008 Feb;31(2):255-60. doi: 10.2337/dc07-0531. Epub 2007 Oct 31.
We examined changes in the prevalence of diabetes, obesity, and overweight in 412,881 Korean men in birth cohorts from 1933 to 1972 over 8 years from 1992 to 2000 and separately analyzed the effects of age, time period, and birth cohort.
The study included male employees of Korean government organizations and schools who were between 20 and 59 years of age in 1992. Diabetes was diagnosed on the basis of self-reports in 1992 or fasting blood glucose levels (>or=126 mg/ml, 7.0 mmol/l). The age-period-cohort model was used to estimate the effects of age, time period, and birth cohort.
In Korean male birth cohorts from 1933 to 1972, the age-specific prevalence of diabetes, obesity, and overweight in men aged 28-59 years increased annually by 0.41% (3.03 to 6.29%), 0.18% (0.70 to 2.16%), and 1.49% (23.48 to 35.41%), respectively, from 1992 to 2000. The relative change in diabetes was largest among the younger cohorts (>400% increase over 8 years) and corresponded to the change in obesity. Apart from the contribution of age, clear cohort and period effects were evident for diabetes, although the magnitude of the effect was slightly less than that for obesity.
Prevention of diabetes through the control of obesity, particularly in young men, clearly needs to be emphasized.
我们调查了1933年至1972年出生队列中的412,881名韩国男性在1992年至2000年的8年间糖尿病、肥胖和超重患病率的变化,并分别分析了年龄、时间段和出生队列的影响。
该研究纳入了1992年年龄在20至59岁之间的韩国政府机构和学校的男性员工。糖尿病根据1992年的自我报告或空腹血糖水平(≥126mg/ml,7.0mmol/l)进行诊断。采用年龄-时期-队列模型来估计年龄、时间段和出生队列的影响。
在1933年至1972年出生的韩国男性队列中,1992年至2000年,28至59岁男性中糖尿病、肥胖和超重的年龄别患病率分别每年增加0.41%(从3.03%增至6.29%)、0.18%(从0.70%增至2.16%)和1.49%(从23.48%增至35.41%)。糖尿病的相对变化在较年轻队列中最大(8年间增加超过400%),且与肥胖的变化相对应。除年龄因素外,糖尿病存在明显的队列和时期效应,尽管效应幅度略小于肥胖。
显然需要强调通过控制肥胖来预防糖尿病,尤其是在年轻男性中。