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犬牙源性黏液瘤的诊断与管理

Diagnosis and management of odontogenic myxoma in a dog.

作者信息

Meyers Bruce, Boy Sonja C, Steenkamp Gerhard

机构信息

Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Gauteng, South Africa.

出版信息

J Vet Dent. 2007 Sep;24(3):166-71. doi: 10.1177/089875640702400304.

Abstract

A three-year-old Jack Russell terrier dog was presented with a large gingival mass of the right mandible extending from the fourth premolar to the first molar teeth. Radiographic examination of the expansile mass revealed moth-eaten, honeycomb-like lyses of the mandible and extended into the mandibular alveolar canal based on computed tomography. The histopathological diagnosis of the biopsy was odontogenic fibromyxoma. Mandibulectomy with resection of the associated soft tissues was performed. Surgical management was curative with no clinical signs of disease 2-years after treatment. These neoplasms are slow growing, locally destructive tumors of odontogenic origin that have been described in the jaw of only one dog. In this paper, the clinico-radiological and pathologic features, diagnostic modalities as well as the factors that might influence treatment outcome of odontogenic myxomas are discussed. These odontogenic tumors are currently excluded from the WHO classification of odontogenic tumors in domestic animals and inclusion in future classifications systems is proposed.

摘要

一只三岁的杰克罗素梗犬被发现右下颌有一个巨大的牙龈肿物,从第四前磨牙延伸至第一磨牙。基于计算机断层扫描,对该膨胀性肿物进行的影像学检查显示下颌骨有虫蚀状、蜂窝状溶解,并延伸至下颌牙槽管。活检的组织病理学诊断为牙源性纤维黏液瘤。实施了下颌骨切除术及相关软组织切除术。治疗两年后,手术治疗取得了治愈效果,无疾病临床症状。这些肿瘤是生长缓慢、具有局部破坏性的牙源性肿瘤,仅在一只犬的颌骨中被描述过。本文讨论了牙源性黏液瘤的临床放射学和病理学特征、诊断方法以及可能影响治疗结果的因素。目前这些牙源性肿瘤被排除在家畜牙源性肿瘤的世界卫生组织分类之外,建议在未来的分类系统中纳入。

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