Ishikawa T, Yamamoto H
Ushiku Animal Hospital, Chiba, Japan.
J Small Anim Pract. 1996 Dec;37(12):597-9. doi: 10.1111/j.1748-5827.1996.tb02339.x.
A 12-year-old male shih tzu dog was diagnosed as having a calcifying epithelial odontogenic tumour. One and a half years prior to presentation, a mass was noticed on the right mandible by the owners. Radiography revealed irregular, faintly radiopaque material within the tumour. A right hemimandibulectomy was performed, based on the clinical diagnosis of osteosarcoma. Histopathological evaluation of the mandibular mass showed that it was composed of a polyhedral odontogenic epithelial cell nest, fibrous stroma, homogeneous eosinophilic material and rounded calcifying material. The eosinophilic material was visualised by staining with Congo red, and observed under green birefringence by polarisation microscopy. Although the tumour had not recurred 12 months after surgery, the dog was euthanased because of aspiratic pharyngitis. The literature on the clinical behaviour of calcifying epithelial odontogenic tumours in dogs and cats is reviewed.
一只12岁的雄性西施犬被诊断患有牙源性钙化上皮瘤。就诊前一年半，主人发现其右下颌有一个肿块。放射检查显示肿瘤内有不规则的、隐约不透射线的物质。基于骨肉瘤的临床诊断，实施了右半下颌骨切除术。对下颌肿块的组织病理学评估显示，它由多面体形牙源性上皮细胞巢、纤维性基质、均质嗜酸性物质和圆形钙化物质组成。通过刚果红染色使嗜酸性物质可视化，并在偏振显微镜下于绿色双折射下观察。尽管术后12个月肿瘤未复发，但该犬因吸入性咽炎而实施了安乐死。本文对犬猫牙源性钙化上皮瘤的临床行为相关文献进行了综述。
