McKeon A, Frye M A, Delanty Norman
Department of Neurology and Clinical Neurosciences, Beaumont Hospital, Dublin, and Royal College of Surgeons in Ireland, Dublin, Ireland.
J Neurol Neurosurg Psychiatry. 2008 Aug;79(8):854-62. doi: 10.1136/jnnp.2007.128322. Epub 2007 Nov 6.
The alcohol withdrawal syndrome (AWS) is a common management problem in hospital practice for neurologists, psychiatrists and general physicians alike. Although some patients have mild symptoms and may even be managed in the outpatient setting, others have more severe symptoms or a history of adverse outcomes that requires close inpatient supervision and benzodiazepine therapy. Many patients with AWS have multiple management issues (withdrawal symptoms, delirium tremens, the Wernicke-Korsakoff syndrome, seizures, depression, polysubstance abuse, electrolyte disturbances and liver disease), which requires a coordinated, multidisciplinary approach. Although AWS may be complex, careful evaluation and available treatments should ensure safe detoxification for most patients.
酒精戒断综合征（AWS）在医院临床实践中是神经科医生、精神科医生和普通内科医生都常遇到的管理问题。虽然有些患者症状较轻，甚至可在门诊处理，但其他患者症状较重或有不良后果史，需要住院密切监护及苯二氮䓬类药物治疗。许多AWS患者存在多种管理问题（戒断症状、震颤谵妄、韦尼克-科尔萨科夫综合征、癫痫发作、抑郁、多种物质滥用、电解质紊乱和肝病），这需要采取协调一致的多学科方法。虽然AWS可能很复杂，但仔细评估和现有治疗措施应能确保大多数患者安全戒毒。
