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鞍上异位生长激素分泌型垂体腺瘤:病例报告

Ectopic suprasellar growth hormone-secreting pituitary adenoma: case report.

作者信息

Guerrero Carlos A, Krayenbühl Niklaus, Husain Muhammad, Krisht Ali F

机构信息

Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

出版信息

Neurosurgery. 2007 Oct;61(4):E879; discussion E879. doi: 10.1227/01.NEU.0000298921.47495.42.

DOI:10.1227/01.NEU.0000298921.47495.42
PMID:17986925
Abstract

OBJECTIVE

Ectopic pituitary adenomas are rare. We present an unusual case of an ectopic growth hormone-secreting pituitary adenoma in the suprasellar space.

CLINICAL PRESENTATION

A 31-year-old man presented with a history of chronic headache and typical clinical signs of acromegaly. Magnetic resonance imaging scans revealed a suprasellar mass not arising from the normal looking pituitary gland.

INTERVENTION

The patient underwent gross total removal of the tumor through a pterional approach. At the time of follow-up, he met the criteria of endocrinological cure. Histological examination showed a growth hormone-secreting pituitary adenoma

CONCLUSION

Although uncommon, growth hormone-secreting pituitary adenomas are encountered in the suprasellar region. They should be added to the differential diagnosis of tumors in this location.

摘要

目的

异位垂体腺瘤较为罕见。我们报告一例位于鞍上区的异位生长激素分泌型垂体腺瘤的罕见病例。

临床表现

一名31岁男性,有慢性头痛病史及典型的肢端肥大症临床体征。磁共振成像扫描显示鞍上有一肿块,并非起源于外观正常的垂体。

干预措施

患者通过翼点入路接受了肿瘤全切术。随访时,他达到了内分泌治愈标准。组织学检查显示为生长激素分泌型垂体腺瘤。

结论

尽管罕见,但鞍上区可出现生长激素分泌型垂体腺瘤。在该部位肿瘤的鉴别诊断中应考虑到这种情况。

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