Socha Aaron M, Long Richard A, Rowley David C
Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.
J Nat Prod. 2007 Nov;70(11):1793-5. doi: 10.1021/np070126a. Epub 2007 Nov 8.
Chemical studies of a Bacillus endophyticus isolated from a Bahamian hypersaline microbial mat led to the isolation of bacillamides B and C, new tryptamide thiazole metabolites. Bioassay-guided fractionation using a HPLC-UV-MS bioassay technique enabled the detection of these trace fermentation products, and their total structures were elucidated by combined spectroscopic techniques.
对从巴哈马高盐度微生物垫中分离出的一种内生芽孢杆菌进行化学研究,从而分离出了杆菌酰胺B和C,这两种新型色胺噻唑代谢产物。使用高效液相色谱-紫外-质谱生物测定技术进行生物测定导向的分级分离,能够检测到这些微量发酵产物,并通过联合光谱技术阐明了它们的完整结构。