MMWR Morb Mortal Wkly Rep. 2007 Nov 9;56(44):1161-4.
In February 2007, the Pennsylvania Department of Health received reports, through routine electronic laboratory disease reporting, of two persons with recent laboratory-confirmed infections with Salmonella enterica serotype Typhimurium. Both persons had reported drinking raw (unpasteurized) milk from the same York County, Pennsylvania, dairy (dairy A). S. Typhimurium isolates from these persons had pulsed-field gel electrophoresis (PFGE) patterns that were indistinguishable by use of the XbaI restriction enzyme. The same month, the Pennsylvania Department of Agriculture (PDA) received reports of illness from raw-milk customers of dairy A. PDA obtained milk samples from the raw-milk bulk tank at dairy A, which yielded S. Typhimurium with a PFGE pattern that was identical to the pattern from patient isolates. On February 26, the Pennsylvania Department of Health and PDA launched an investigation to determine the source and scope of the outbreak. This report summarizes the findings of that investigation, which determined that 29 cases of diarrheal illness caused by S. Typhimurium were associated with consumption of raw milk or raw-milk products from dairy A. The findings underscore the need to inform policymakers and the public of the potential health risks associated with raw-milk consumption.
2007年2月，宾夕法尼亚州卫生部通过常规电子实验室疾病报告系统收到报告，称有两人近期经实验室确诊感染鼠伤寒沙门氏菌。这两人均报告饮用了来自宾夕法尼亚州约克县同一家奶牛场（A奶牛场）的生（未巴氏消毒）牛奶。从这两人身上分离出的鼠伤寒沙门氏菌菌株，经XbaI限制性内切酶处理后的脉冲场凝胶电泳（PFGE）图谱无法区分。同月，宾夕法尼亚州农业部（PDA）收到A奶牛场生牛奶消费者的疾病报告。PDA从A奶牛场的生牛奶储存罐中采集了牛奶样本，从中检测出的鼠伤寒沙门氏菌的PFGE图谱与患者菌株的图谱相同。2月26日，宾夕法尼亚州卫生部和PDA展开调查，以确定此次疫情的源头和范围。本报告总结了该调查结果，调查确定29例由鼠伤寒沙门氏菌引起的腹泻病与饮用A奶牛场的生牛奶或生牛奶制品有关。这些结果强调了有必要告知政策制定者和公众饮用生牛奶相关的潜在健康风险。
