精原细胞瘤经根治性腹膜后放疗后发生的肾盂鳞状细胞癌。

Squamous cell carcinoma of the renal pelvis after curative retroperitoneal radiotherapy for seminoma.

作者信息

O'Daly Brendan J, O'Brien Matthew Frank, Dowling Catherine M, Crotty Thomas B, Watson Alan J, Moriarty Michael J, Mulvin David W

机构信息

Department of Urology, St. Vincent's University Hospital, Dublin, Ireland.

出版信息

Urology. 2007 Oct;70(4):812.e3-6. doi: 10.1016/j.urology.2007.07.043.

DOI:10.1016/j.urology.2007.07.043

PMID:17991576

Abstract

We report the case of a 71-year-old male who presented with squamous cell carcinoma of the renal pelvis in a solitary functioning kidney, 34 years after orchidectomy and adjuvant retroperitoneal radiotherapy for stage II seminoma. This rare second malignancy occurred in the radiation treatment field. Second malignancies are an uncommon but serious sequela of radiotherapy, with potential for significant health problems in patients with complete remission of primary disease. To our knowledge, this is the first report of squamous cell carcinoma of the renal pelvis occurring after radiation treatment.

摘要

我们报告了一例71岁男性患者的病例，该患者在因II期精原细胞瘤接受睾丸切除及辅助性腹膜后放疗34年后，出现了孤立功能肾的肾盂鳞状细胞癌。这种罕见的第二原发恶性肿瘤发生在放疗区域。第二原发恶性肿瘤是放疗少见但严重的后遗症，对于原发疾病完全缓解的患者有导致重大健康问题的可能。据我们所知，这是关于放疗后发生肾盂鳞状细胞癌的首例报告。