Johnston Christopher A, Temple Brenda R, Chen Jin-Gui, Gao Yajun, Moriyama Etsuko N, Jones Alan M, Siderovski David P, Willard Francis S
Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27599, USA.
Science. 2007 Nov 9;318(5852):914; author reply 914. doi: 10.1126/science.1143230.
Liu et al. (Reports, 23 March 2007, p. 1712) reported that the Arabidopsis thaliana gene GCR2 encodes a seven-transmembrane, G protein-coupled receptor for abscisic acid. We argue that GCR2 is not likely to be a transmembrane protein nor a G protein-coupled receptor. Instead, GCR2 is most likely a plant homolog of bacterial lanthionine synthetases.
刘等人（《科学》，2007年3月23日，第1712页）报道，拟南芥基因GCR2编码一种七跨膜的脱落酸G蛋白偶联受体。我们认为GCR2不太可能是跨膜蛋白，也不是G蛋白偶联受体。相反，GCR2很可能是细菌丙氨酸合成酶的植物同源物。
