Arirachakaran P, Luengpailin S, Banas J A, Mazurkiewicz J E, Benjavongkulchai E
Chulalongkorn University, Bangkok, Thailand.
Caries Res. 2007;41(6):497-502. doi: 10.1159/000110882. Epub 2007 Nov 8.
Streptococcus mutans, an agent of dental caries, was tested for growth in the presence or absence of manganese (Mn), since studies have linked Mn levels with cariogenic potential. Seven S. mutans serotype c strains were grown in chemically defined medium under different atmospheric conditions: 5% CO2, O2-enriched 5% CO2 (shaking) and anaerobic. There was significant strain variability with respect to Mn requirements under the various conditions tested. Both sucrose-dependent and sucrose-independent biofilm growth by strain UA159 were affected by the absence of Mn. S. mutans strains show highly variable responses to both high and low Mn concentrations.
变形链球菌是导致龋齿的病原体，由于有研究表明锰（Mn）水平与致龋潜力有关，因此对其在有无锰的情况下的生长情况进行了测试。七株变形链球菌c血清型菌株在化学限定培养基中于不同的大气条件下培养：5%二氧化碳、富氧5%二氧化碳（振荡）和厌氧。在所测试的各种条件下，菌株对锰的需求存在显著差异。菌株UA159的蔗糖依赖性和非蔗糖依赖性生物膜生长均受到缺锰的影响。变形链球菌菌株对高浓度和低浓度锰的反应都高度可变。
