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复发性流产——孕早期支持性治疗后的结局

Recurrent miscarriage--outcome after supportive care in early pregnancy.

作者信息

Liddell H S, Pattison N S, Zanderigo A

机构信息

National Women's Hospital, Auckland, New Zealand.

出版信息

Aust N Z J Obstet Gynaecol. 1991 Nov;31(4):320-2. doi: 10.1111/j.1479-828x.1991.tb02811.x.

Abstract

One hundred and thirty three couples were investigated at a recurrent miscarriage clinic. In their next pregnancy 42 women (Group 1) with unexplained recurrent miscarriage were managed with a programme of formal emotional support and close supervision at an early pregnancy clinic. Two women were seen in 2 pregnancies (44 supervised pregnancies); 86% (38 of 44) of these pregnancies were successful. Four of the 6 miscarriages had an identifiable causal factor. Nine women (Group 2), also with unexplained recurrent miscarriage, acted as a control group. After initial investigation they were reassured and returned to the care of their family practitioner and did not receive formal supportive care in their subsequent pregnancy; 33% (3 of 9) of these pregnancies were successful (p = 0.005; Fishers Exact Test). Whilst acknowledging that there is a significant spontaneous cure rate in this condition, emotional support seems to be important in the prevention of unexplained recurrent miscarriage, giving results as good as any currently accepted therapy.

摘要

在一家复发性流产诊所对133对夫妇进行了调查。在他们的下一次妊娠中,42名不明原因复发性流产的女性(第1组)在一家早孕诊所接受了正式情感支持和密切监测的方案管理。有两名女性经历了两次妊娠(共44次受监测妊娠);其中86%(44次中的38次)妊娠成功。6次流产中有4次有可识别的因果因素。另外9名同样不明原因复发性流产的女性(第2组)作为对照组。在初步检查后,她们得到了安慰,并回到家庭医生处接受治疗,在随后的妊娠中没有接受正式的支持性护理;这些妊娠中有33%(9次中的3次)成功(p = 0.005;Fisher精确检验)。虽然承认这种情况有显著的自然治愈率,但情感支持似乎对预防不明原因复发性流产很重要,其效果与目前任何公认的治疗方法一样好。

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