Liddell H S, Pattison N S, Zanderigo A
National Women's Hospital, Auckland, New Zealand.
Aust N Z J Obstet Gynaecol. 1991 Nov;31(4):320-2. doi: 10.1111/j.1479-828x.1991.tb02811.x.
One hundred and thirty three couples were investigated at a recurrent miscarriage clinic. In their next pregnancy 42 women (Group 1) with unexplained recurrent miscarriage were managed with a programme of formal emotional support and close supervision at an early pregnancy clinic. Two women were seen in 2 pregnancies (44 supervised pregnancies); 86% (38 of 44) of these pregnancies were successful. Four of the 6 miscarriages had an identifiable causal factor. Nine women (Group 2), also with unexplained recurrent miscarriage, acted as a control group. After initial investigation they were reassured and returned to the care of their family practitioner and did not receive formal supportive care in their subsequent pregnancy; 33% (3 of 9) of these pregnancies were successful (p = 0.005; Fishers Exact Test). Whilst acknowledging that there is a significant spontaneous cure rate in this condition, emotional support seems to be important in the prevention of unexplained recurrent miscarriage, giving results as good as any currently accepted therapy.
在一家复发性流产诊所对133对夫妇进行了调查。在他们的下一次妊娠中，42名不明原因复发性流产的女性（第1组）在一家早孕诊所接受了正式情感支持和密切监测的方案管理。有两名女性经历了两次妊娠（共44次受监测妊娠）；其中86%（44次中的38次）妊娠成功。6次流产中有4次有可识别的因果因素。另外9名同样不明原因复发性流产的女性（第2组）作为对照组。在初步检查后，她们得到了安慰，并回到家庭医生处接受治疗，在随后的妊娠中没有接受正式的支持性护理；这些妊娠中有33%（9次中的3次）成功（p = 0.005；Fisher精确检验）。虽然承认这种情况有显著的自然治愈率，但情感支持似乎对预防不明原因复发性流产很重要，其效果与目前任何公认的治疗方法一样好。
